GenomeNet

Database: UniProt
Entry: P15216
LinkDB: P15216
Original site: P15216 
ID   FBP2_STRPU              Reviewed;         325 AA.
AC   P15216;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1990, sequence version 1.
DT   16-JAN-2019, entry version 74.
DE   RecName: Full=Fibropellin-2;
DE   AltName: Full=Epidermal growth factor-related protein 2;
DE   AltName: Full=Fibropellin II;
DE   Flags: Precursor;
GN   Name=EGF2;
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
OC   Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2814501; DOI=10.1126/science.2814501;
RA   Yang O., Angerer L.M., Angerer R.C.;
RT   "Unusual pattern of accumulation of mRNA encoding EGF-related protein
RT   in sea urchin embryos.";
RL   Science 246:806-808(1989).
DR   EMBL; M29004; AAA30044.1; -; mRNA.
DR   PIR; A40084; A40084.
DR   RefSeq; NP_999696.1; NM_214531.1.
DR   UniGene; Spu.1548; -.
DR   ProteinModelPortal; P15216; -.
DR   SMR; P15216; -.
DR   GeneID; 373304; -.
DR   KEGG; spu:373304; -.
DR   CTD; 373304; -.
DR   OrthoDB; 1606942at2759; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR   InterPro; IPR013032; EGF-like_CS.
DR   InterPro; IPR000742; EGF-like_dom.
DR   Pfam; PF00008; EGF; 1.
DR   Pfam; PF07645; EGF_CA; 1.
DR   SMART; SM00181; EGF; 4.
DR   PROSITE; PS01186; EGF_2; 4.
DR   PROSITE; PS50026; EGF_3; 2.
PE   2: Evidence at transcript level;
KW   Complete proteome; Disulfide bond; EGF-like domain;
KW   Reference proteome; Repeat; Signal.
FT   SIGNAL        1     17       {ECO:0000255}.
FT   CHAIN        18    325       Fibropellin-2.
FT                                /FTId=PRO_0000007587.
FT   DOMAIN       48     91       EGF-like 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DOMAIN      107    152       EGF-like 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DOMAIN      178    224       EGF-like 3. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DOMAIN      252    293       EGF-like 4. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00076}.
FT   DISULFID     52     65       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID     59     75       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID     77     90       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    111    124       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    118    137       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    139    151       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    182    195       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    189    209       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    211    223       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    256    269       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    263    278       {ECO:0000255|PROSITE-ProRule:PRU00076}.
FT   DISULFID    280    292       {ECO:0000255|PROSITE-ProRule:PRU00076}.
SQ   SEQUENCE   325 AA;  36898 MW;  F09BA8805654C7AC CRC64;
     MQFNLVFVVA VIGVGMVAAD ENLMSKLQMA LKSMLNENEE LQMQSRDTKG QCESDTNKCN
     NHGTCIEGRW GTYYCKCEMP FRVGIPDSSC YPPPEGKKDL EIEARDSENR CLSDTSNCDG
     HGICQLSTFG RNERYICFCA LGFRNNNYGG CSPYTPREIE FLSYVARDLE LEMLTRDSLG
     RCKSDTHNCD EAGQCVTKTY GRYAGEYICV CNHGYRNNAY GGCSPMTTRE IEYLDMLARE
     EQMQMLVRKY YSLSECSQGT NDCNENGECV EEDGKYWCEC GEGYEENEDG GCSPIVTRAT
     EVDDDDFAER KKEIMRQLAE FLQEE
//
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