ID SEGE_BPT4 Reviewed; 205 AA.
AC P18060; Q9T0T9;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 19-DEC-2001, sequence version 2.
DT 08-NOV-2023, entry version 98.
DE RecName: Full=Putative endonuclease segE;
DE EC=3.1.-.-;
DE AltName: Full=Endodeoxyribonuclease segE;
GN Name=segE; Synonyms=hoc.2;
OS Enterobacteria phage T4 (Bacteriophage T4).
OC Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC Straboviridae; Tevenvirinae; Tequatrovirus.
OX NCBI_TaxID=10665;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2377482; DOI=10.1093/nar/18.14.4277;
RA Kaliman A.V., Khasanova M.A., Kryukov V.M., Tanyashin V.I., Bayev A.A.;
RT "The nucleotide sequence of the region of bacteriophage T4 inh(lip)-hoc
RT genes.";
RL Nucleic Acids Res. 18:4277-4277(1990).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT "Bacteriophage T4 genome.";
RL Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN [3]
RP IDENTIFICATION, AND POSSIBLE FUNCTION.
RX PubMed=1631169; DOI=10.1073/pnas.89.14.6658;
RA Sharma M., Ellis R.L., Hinton D.M.;
RT "Identification of a family of bacteriophage T4 genes encoding proteins
RT similar to those present in group I introns of fungi and phage.";
RL Proc. Natl. Acad. Sci. U.S.A. 89:6658-6662(1992).
CC -!- FUNCTION: Probably involved in the movement of the endonuclease-
CC encoding DNA.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC -!- SIMILARITY: To endonucleases of group I introns of fungi and phage.
CC {ECO:0000305}.
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DR EMBL; X14869; CAA33013.1; -; Genomic_DNA.
DR EMBL; AF158101; AAD42658.1; -; Genomic_DNA.
DR PIR; JQ0565; S10497.
DR RefSeq; NP_049795.1; NC_000866.4.
DR SMR; P18060; -.
DR REBASE; 3006; F-TevII.
DR GeneID; 1258802; -.
DR KEGG; vg:1258802; -.
DR OrthoDB; 7844at10239; -.
DR Proteomes; UP000009087; Segment.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd10444; GIY-YIG_SegABCDEFG; 1.
DR Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR InterPro; IPR000305; GIY-YIG_endonuc.
DR InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR InterPro; IPR045566; SegE_GIY-YIG.
DR Pfam; PF19835; SegE_GIY-YIG; 1.
DR SMART; SM00465; GIYc; 1.
DR SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR PROSITE; PS50164; GIY_YIG; 1.
PE 4: Predicted;
KW Endonuclease; Hydrolase; Magnesium; Nuclease; Reference proteome.
FT CHAIN 1..205
FT /note="Putative endonuclease segE"
FT /id="PRO_0000164984"
FT DOMAIN 1..84
FT /note="GIY-YIG"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00977"
FT CONFLICT 87
FT /note="G -> S (in Ref. 1; CAA33013)"
FT /evidence="ECO:0000305"
FT CONFLICT 127
FT /note="T -> S (in Ref. 1; CAA33013)"
FT /evidence="ECO:0000305"
FT CONFLICT 135
FT /note="G -> R (in Ref. 1; CAA33013)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 205 AA; 22895 MW; 614AAEFF992CC2B7 CRC64;
MYHFVYETTN LINGKKYIGK HSTDDLNDGY LGSGKAIQQA IKKYGENNFS RTILKEFKTS
EEAYMYEEEI ITPELIKSKN YYNMKPGGIG GIVMTTDVIA KMKESSAKRF ENSPGTVLGK
TCYTNGTKNI FIKPGELVPE GFVKGMVHPN RKSRKGCKVK PTTTGTFWVN NGAINKLIQP
DGIIPDGFIK GRLMKRDSKG KFSKA
//
