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Database: UniProt
Entry: P28765
LinkDB: P28765
Original site: P28765 
ID   SODM_PALVU              Reviewed;         144 AA.
AC   P28765;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   05-DEC-2018, entry version 83.
DE   RecName: Full=Superoxide dismutase [Mn], mitochondrial;
DE            EC=1.15.1.1;
DE   Flags: Fragment;
OS   Palinurus vulgaris (European spiny lobster).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata;
OC   Achelata; Palinuroidea; Palinuridae; Palinurus.
OX   NCBI_TaxID=6733;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1556751;
RA   Smith M.W., Doolittle R.F.;
RT   "A comparison of evolutionary rates of the two major kinds of
RT   superoxide dismutase.";
RL   J. Mol. Evol. 34:175-184(1992).
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological
CC       systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC       Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000250};
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix.
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000305}.
DR   EMBL; X64063; CAA45419.1; -; mRNA.
DR   PIR; S23659; S23659.
DR   ProteinModelPortal; P28765; -.
DR   SMR; P28765; -.
DR   GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
PE   2: Evidence at transcript level;
KW   Manganese; Metal-binding; Mitochondrion; Oxidoreductase.
FT   CHAIN        <1   >144       Superoxide dismutase [Mn], mitochondrial.
FT                                /FTId=PRO_0000159960.
FT   METAL        10     10       Manganese. {ECO:0000250}.
FT   METAL        58     58       Manganese. {ECO:0000250}.
FT   METAL       143    143       Manganese. {ECO:0000250}.
FT   NON_TER       1      1
FT   NON_TER     144    144
SQ   SEQUENCE   144 AA;  15505 MW;  F180CE5236B53686 CRC64;
     HISEMIMQIH HTKHHQAYIN NLKACTEKLK QAEQANDVAA MNALLPAIKF NGGGHINHTI
     FWTNMAPSAG GEPAGPVADA ITKEFGSFQA FKDKFSTASV GVKGSGWGWL GYCPKNDKLA
     VATCQNQDPL QLTHGLIPLL GLDV
//
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