ID RRT13_YEAST Reviewed; 185 AA.
AC P40042; D3DLX1;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 27-MAR-2024, entry version 156.
DE RecName: Full=Regulator of rDNA transcription protein 13;
GN Name=RRT13; OrderedLocusNames=YER066W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169868;
RA Dietrich F.S., Mulligan J.T., Hennessy K.M., Yelton M.A., Allen E.,
RA Araujo R., Aviles E., Berno A., Brennan T., Carpenter J., Chen E.,
RA Cherry J.M., Chung E., Duncan M., Guzman E., Hartzell G., Hunicke-Smith S.,
RA Hyman R.W., Kayser A., Komp C., Lashkari D., Lew H., Lin D., Mosedale D.,
RA Nakahara K., Namath A., Norgren R., Oefner P., Oh C., Petel F.X.,
RA Roberts D., Sehl P., Schramm S., Shogren T., Smith V., Taylor P., Wei Y.,
RA Botstein D., Davis R.W.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome V.";
RL Nature 387:78-81(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP FUNCTION.
RX PubMed=19270272; DOI=10.1534/genetics.108.100313;
RA Hontz R.D., Niederer R.O., Johnson J.M., Smith J.S.;
RT "Genetic identification of factors that modulate ribosomal DNA
RT transcription in Saccharomyces cerevisiae.";
RL Genetics 182:105-119(2009).
CC -!- FUNCTION: May be involved in the modulation of rDNA transcription.
CC {ECO:0000269|PubMed:19270272}.
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DR EMBL; U18813; AAB64602.1; -; Genomic_DNA.
DR EMBL; BK006939; DAA07725.1; -; Genomic_DNA.
DR PIR; S50569; S50569.
DR RefSeq; NP_010988.1; NM_001178957.1.
DR AlphaFoldDB; P40042; -.
DR SMR; P40042; -.
DR BioGRID; 36809; 47.
DR DIP; DIP-2848N; -.
DR IntAct; P40042; 2.
DR MINT; P40042; -.
DR STRING; 4932.YER066W; -.
DR PaxDb; 4932-YER066W; -.
DR PeptideAtlas; P40042; -.
DR EnsemblFungi; YER066W_mRNA; YER066W; YER066W.
DR GeneID; 856796; -.
DR KEGG; sce:YER066W; -.
DR AGR; SGD:S000000868; -.
DR SGD; S000000868; RRT13.
DR VEuPathDB; FungiDB:YER066W; -.
DR eggNOG; KOG0274; Eukaryota.
DR GeneTree; ENSGT00940000174696; -.
DR HOGENOM; CLU_1462435_0_0_1; -.
DR InParanoid; P40042; -.
DR OMA; NTITALX; -.
DR OrthoDB; 587035at2759; -.
DR BioCyc; YEAST:G3O-30240-MONOMER; -.
DR BioGRID-ORCS; 856796; 0 hits in 10 CRISPR screens.
DR PRO; PR:P40042; -.
DR Proteomes; UP000002311; Chromosome V.
DR RNAct; P40042; Protein.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 2.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 2.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW WD repeat.
FT CHAIN 1..185
FT /note="Regulator of rDNA transcription protein 13"
FT /id="PRO_0000051472"
FT REPEAT 9..48
FT /note="WD 1"
FT REPEAT 71..108
FT /note="WD 2"
FT REPEAT 111..148
FT /note="WD 3"
SQ SEQUENCE 185 AA; 20686 MW; A07DCF8B3CA30399 CRC64;
MKCLYILSGH TDRIYSTIYD HERKRCISAS MDTTIRIWDL ENIRNNGECS YATNSASPCA
KILGAMYTLR GHRALVGLLG LSDKFLVSAS VDGSIRCWDA NTYFLKHFFD HTQLNTITAL
HVSDEVLVSG SEGLLNIYDL NSGLLVRSDT LSGADNVWNV SFKDNTLVAA VERDKRNLLE
ILDFS
//
