GenomeNet

Database: UniProt
Entry: P46239
LinkDB: P46239
Original site: P46239 
ID   GUNF_FUSOX              Reviewed;         385 AA.
AC   P46239;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-OCT-2017, entry version 87.
DE   RecName: Full=Putative endoglucanase type F;
DE            EC=3.2.1.4;
DE   AltName: Full=Cellulase;
DE   AltName: Full=Endo-1,4-beta-glucanase;
DE   Flags: Precursor;
OS   Fusarium oxysporum (Fusarium vascular wilt).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
OC   Fusarium; Fusarium oxysporum species complex.
OX   NCBI_TaxID=5507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=7959045; DOI=10.1016/0378-1119(94)90878-8;
RA   Sheppard P.O., Grant F.J., Oort P.J., Sprecher C.A., Foster D.C.,
RA   Hagen F.S., Upshall A., McKnight G.L., O'Hara P.J.;
RT   "The use of conserved cellulase family-specific sequences to clone
RT   cellulase homologue cDNAs from Fusarium oxysporum.";
RL   Gene 150:163-167(1994).
CC   -!- CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-beta-D-glucosidic
CC       linkages in cellulose, lichenin and cereal beta-D-glucans.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 10 (cellulase F)
CC       family. {ECO:0000305}.
DR   EMBL; L29380; AAA65588.1; -; mRNA.
DR   ProteinModelPortal; P46239; -.
DR   SMR; P46239; -.
DR   CAZy; CBM1; Carbohydrate-Binding Module Family 1.
DR   CAZy; GH10; Glycoside Hydrolase Family 10.
DR   PRIDE; P46239; -.
DR   eggNOG; ENOG410IVNE; Eukaryota.
DR   eggNOG; COG3693; LUCA.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR   GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR035971; CBD_sf.
DR   InterPro; IPR000254; Cellulose-bd_dom_fun.
DR   InterPro; IPR001000; GH10.
DR   InterPro; IPR031158; GH10_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00734; CBM_1; 1.
DR   Pfam; PF00331; Glyco_hydro_10; 1.
DR   PRINTS; PR00134; GLHYDRLASE10.
DR   ProDom; PD001821; CBD_fun; 1.
DR   SMART; SM00236; fCBD; 1.
DR   SMART; SM00633; Glyco_10; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
DR   SUPFAM; SSF57180; SSF57180; 1.
DR   PROSITE; PS00562; CBM1_1; 1.
DR   PROSITE; PS51164; CBM1_2; 1.
DR   PROSITE; PS00591; GH10_1; 1.
DR   PROSITE; PS51760; GH10_2; 1.
PE   2: Evidence at transcript level;
KW   Carbohydrate metabolism; Cellulose degradation; Glycosidase;
KW   Hydrolase; Polysaccharide degradation; Signal.
FT   SIGNAL        1     19       {ECO:0000255}.
FT   CHAIN        20    385       Putative endoglucanase type F.
FT                                /FTId=PRO_0000007961.
FT   DOMAIN       23     53       CBM1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00597}.
FT   DOMAIN      105    384       GH10. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01096}.
FT   REGION       53     84       Linker.
FT   ACT_SITE    210    210       Proton donor. {ECO:0000250}.
FT   ACT_SITE    321    321       Nucleophile. {ECO:0000255|PROSITE-
FT                                ProRule:PRU10061}.
SQ   SEQUENCE   385 AA;  41225 MW;  B3C3807C07D3C0EC CRC64;
     MHTLSVLLAL APVSALAQAP IWGQCGGNGW TGATTCASGL KCEKINDWYY QCVPGSGGSE
     PQPSSTQGGG TPQPTGGNSG GTGLDAKFKA KGKQYFGTEI DHYHLNNNPL INIVKAQFGQ
     VTCENSMKWD AIEPSRNSFT FSNADKVVDF ATQNGKLIRG HTLLWHSQLP QWVQNINDRS
     TLTAVIENHV KTMVTRYKGK ILQWDVVNNE IFAEDGNLRD SVFSRVLGED FVGIAFRAAR
     AADPAAKLYI NDYNLDKSDY AKVTRGMVAH VNKWIAAGIP IDGIGSQGHL AAPSGWNPAS
     GVPAALRALA ASDAKEIAIT ELDIAGASAN DYLTVMNACL AVPKCVGITV WGVSDKDSWR
     PGDNPLLYDS NYQPKAAFNA LANAL
//
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