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Database: UniProt
Entry: P52111
LinkDB: P52111
Original site: P52111 
ID   GLPD_PSEAE              Reviewed;         512 AA.
AC   P52111;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   08-DEC-2000, sequence version 2.
DT   10-APR-2019, entry version 108.
DE   RecName: Full=Glycerol-3-phosphate dehydrogenase;
DE            EC=1.1.5.3;
GN   Name=glpD; OrderedLocusNames=PA3584;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /
OS   JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CD10;
RX   PubMed=8157588; DOI=10.1128/jb.176.8.2184-2193.1994;
RA   Schweizer H.P., Po C.;
RT   "Cloning and nucleotide sequence of the glpD gene encoding sn-
RT   glycerol-3-phosphate dehydrogenase of Pseudomonas aeruginosa.";
RL   J. Bacteriol. 176:2184-2193(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 /
RC   1C / PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T.,
RA   Reizer J., Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an
RT   opportunistic pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinone + sn-glycerol 3-phosphate = a quinol +
CC         dihydroxyacetone phosphate; Xref=Rhea:RHEA:18977,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:57597, ChEBI:CHEBI:57642,
CC         ChEBI:CHEBI:132124; EC=1.1.5.3;
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the FAD-dependent glycerol-3-phosphate
CC       dehydrogenase family. {ECO:0000305}.
DR   EMBL; L06231; AAA81584.1; -; Genomic_DNA.
DR   EMBL; AE004091; AAG06972.1; -; Genomic_DNA.
DR   PIR; A55207; A55207.
DR   PIR; B83197; B83197.
DR   RefSeq; NP_252274.1; NC_002516.2.
DR   RefSeq; WP_003098460.1; NZ_QZGE01000001.1.
DR   ProteinModelPortal; P52111; -.
DR   SMR; P52111; -.
DR   PaxDb; P52111; -.
DR   PRIDE; P52111; -.
DR   EnsemblBacteria; AAG06972; AAG06972; PA3584.
DR   GeneID; 880179; -.
DR   KEGG; pae:PA3584; -.
DR   PATRIC; fig|208964.12.peg.3751; -.
DR   PseudoCAP; PA3584; -.
DR   eggNOG; ENOG4105C6V; Bacteria.
DR   eggNOG; COG0578; LUCA.
DR   HOGENOM; HOG000004811; -.
DR   InParanoid; P52111; -.
DR   KO; K00111; -.
DR   OMA; MDNPTVK; -.
DR   PhylomeDB; P52111; -.
DR   BioCyc; PAER208964:G1FZ6-3653-MONOMER; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IBA:GO_Central.
DR   GO; GO:0004368; F:glycerol-3-phosphate dehydrogenase (quinone) activity; IBA:GO_Central.
DR   GO; GO:0004367; F:glycerol-3-phosphate dehydrogenase [NAD+] activity; IBA:GO_Central.
DR   GO; GO:0052591; F:sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006071; P:glycerol metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046168; P:glycerol-3-phosphate catabolic process; IBA:GO_Central.
DR   Gene3D; 1.10.8.870; -; 1.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR031656; DAO_C.
DR   InterPro; IPR038299; DAO_C_sf.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR000447; G3P_DH_FAD-dep.
DR   PANTHER; PTHR11985; PTHR11985; 1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16901; DAO_C; 1.
DR   PRINTS; PR01001; FADG3PDH.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS00977; FAD_G3PDH_1; 1.
DR   PROSITE; PS00978; FAD_G3PDH_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; FAD; Flavoprotein; Glycerol metabolism;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN         1    512       Glycerol-3-phosphate dehydrogenase.
FT                                /FTId=PRO_0000126104.
FT   NP_BIND      16     44       FAD. {ECO:0000255}.
FT   CONFLICT     77     78       EA -> DT (in Ref. 1; AAA81584).
FT                                {ECO:0000305}.
FT   CONFLICT    133    140       GLRFTGSS -> ACVHRQQ (in Ref. 1;
FT                                AAA81584). {ECO:0000305}.
FT   CONFLICT    180    208       RTRCVSARRSKGLWHLHLERSDGSLYSIR -> APAASAPV
FT                                AARDSGTCTWSAATAACIRS (in Ref. 1;
FT                                AAA81584). {ECO:0000305}.
FT   CONFLICT    425    430       LRWART -> PALGAH (in Ref. 1; AAA81584).
FT                                {ECO:0000305}.
SQ   SEQUENCE   512 AA;  57135 MW;  DFF734821ABD730C CRC64;
     MSQAHTPSAP LAEVYDVAVV GGGINGVGIA ADAAGRGLSV FLCEQHDLAQ HTSSASSKLI
     HGGLRYLEHY EFRLVREALA EREVLLAKAP HIVKPLRFVL PHRPHLRPAW MIRAGLFLYD
     HLGKREKLPA SRGLRFTGSS PLKAEIRRGF EYSDCAVDDA RLVVLNAISA REHGAHVHTR
     TRCVSARRSK GLWHLHLERS DGSLYSIRAR ALVNAAGPWV ARFIQDDLKQ KSPYGIRLIQ
     GSHIIVPKLY EGEHAYILQN EDRRIVFAIP YLDRFTMIGT TDREYQGDPA KVAISEEETA
     YLLQVVNAHF KQQLAAADIL HSFAGVRPLC DDESDEPSAI TRDYTLSLSA GNGEPPLLSV
     FGGKLTTYRK LAESALTQLQ PFFANLGPAW TAKAPLPGGE QMQSVEALTE QLANRYAWLD
     RELALRWART YGTRVWRLLD GVNGEADLGE HLGGGLYARE VDYLCKHEWA QDAEDILWRR
     SKLGLFLSPS QQVRLGQYLQ SEHPHRPRVH AA
//
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