ID P71912_MYCTU Unreviewed; 139 AA.
AC P71912; F2GHN1; I6Y9B0; L0TB78;
DT 01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT 05-JUL-2004, sequence version 4.
DT 27-MAR-2024, entry version 124.
DE SubName: Full=Conserved transmembrane protein {ECO:0000313|EMBL:CCP45229.1};
GN OrderedLocusNames=Rv2437 {ECO:0000313|EMBL:CCP45229.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP45229.1, ECO:0000313|Proteomes:UP000001584};
RN [1] {ECO:0000313|EMBL:CCP45229.1, ECO:0000313|Proteomes:UP000001584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL123456; CCP45229.1; -; Genomic_DNA.
DR RefSeq; NP_216953.1; NC_000962.3.
DR RefSeq; WP_003412563.1; NZ_NVQJ01000024.1.
DR AlphaFoldDB; P71912; -.
DR SMR; P71912; -.
DR STRING; 83332.Rv2437; -.
DR PaxDb; 83332-Rv2437; -.
DR DNASU; 885906; -.
DR GeneID; 45426427; -.
DR GeneID; 885906; -.
DR KEGG; mtu:Rv2437; -.
DR PATRIC; fig|83332.111.peg.2728; -.
DR eggNOG; COG2020; Bacteria.
DR InParanoid; P71912; -.
DR OrthoDB; 941586at2; -.
DR PhylomeDB; P71912; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR Gene3D; 1.20.120.1630; -; 1.
DR InterPro; IPR007318; Phopholipid_MeTrfase.
DR PANTHER; PTHR43847; BLL3993 PROTEIN; 1.
DR PANTHER; PTHR43847:SF1; BLL3993 PROTEIN; 1.
DR Pfam; PF04191; PEMT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001584};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 139 AA; 15315 MW; 842BF116C0E102EC CRC64;
MLQRTNVVQP LNTLRMVWIQ VAGIIPATAG IAATVYAQLA MGDSWRIGVD EQENTTLVRT
GPFKWVRHPI YTAMMAFGLG LLLVTPNLVA LAGFILLVAT LEVHVRRVEE PYLLRTHSAV
YRGYTASVGR FVPGVGLIR
//
