ID P90910_CAEEL Unreviewed; 232 AA.
AC P90910;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 21-AUG-2007, sequence version 2.
DT 27-MAR-2024, entry version 118.
DE RecName: Full=Actin maturation protease {ECO:0000256|ARBA:ARBA00034848};
DE AltName: Full=Actin aminopeptidase ACTMAP {ECO:0000256|ARBA:ARBA00034908};
GN ORFNames=CELE_K07A1.3 {ECO:0000313|EMBL:CAB03165.2}, K07A1.3
GN {ECO:0000313|EMBL:CAB03165.2, ECO:0000313|WormBase:K07A1.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CAB03165.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CAB03165.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CAB03165.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-
CC [protein] = N-acetyl-L-cysteine + N-terminal L-aspartyl-[protein];
CC Xref=Rhea:RHEA:74579, Rhea:RHEA-COMP:12669, Rhea:RHEA-COMP:18395,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:64720, ChEBI:CHEBI:78236,
CC ChEBI:CHEBI:193599; Evidence={ECO:0000256|ARBA:ARBA00034621};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:74580;
CC Evidence={ECO:0000256|ARBA:ARBA00034621};
CC -!- SIMILARITY: Belongs to the ACTMAP family.
CC {ECO:0000256|ARBA:ARBA00034725}.
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DR EMBL; BX284601; CAB03165.2; -; Genomic_DNA.
DR RefSeq; NP_492543.2; NM_060142.5.
DR AlphaFoldDB; P90910; -.
DR SMR; P90910; -.
DR STRING; 6239.K07A1.3.1; -.
DR EPD; P90910; -.
DR PaxDb; 6239-K07A1-3; -.
DR PeptideAtlas; P90910; -.
DR EnsemblMetazoa; K07A1.3.1; K07A1.3.1; WBGene00010610.
DR GeneID; 172795; -.
DR KEGG; cel:CELE_K07A1.3; -.
DR UCSC; K07A1.3; c. elegans.
DR AGR; WB:WBGene00010610; -.
DR WormBase; K07A1.3; CE41247; WBGene00010610; -.
DR eggNOG; ENOG502QQQD; Eukaryota.
DR GeneTree; ENSGT00390000012368; -.
DR HOGENOM; CLU_077492_0_0_1; -.
DR InParanoid; P90910; -.
DR OMA; NGPTCGL; -.
DR OrthoDB; 2874026at2759; -.
DR PhylomeDB; P90910; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00010610; Expressed in pharyngeal muscle cell (C elegans) and 3 other cell types or tissues.
DR GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR040043; ACTMAP.
DR PANTHER; PTHR28631; UPF0692 PROTEIN C19ORF54; 1.
DR PANTHER; PTHR28631:SF1; UPF0692 PROTEIN C19ORF54; 1.
DR Pfam; PF21646; ACTMAP-like_C; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000313|EMBL:CAB03165.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940}.
SQ SEQUENCE 232 AA; 25796 MW; 5B993E213A7BB732 CRC64;
MDNAFDFQSL PMITQIRLTS FTGEFGGQVC LNTNKITPRQ QKGPTCGLVA ISMCLEHFGI
KTNPETILEK AKEMGFTKQG EMYSAESLAS LTNEFLPNSS KIRKMPSPKE FTQSICDGKQ
MLIAYDCGPN YQPVYVRGHS AHWLLACGFV KKQEVDGFVE TRETVAETDE IAIIGYQGKS
TNLNVFPFNE VVASNAQLLE AGLKRDPSEY IIPDPHNLSE IRNCVVEVCI NN
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