ID P91350_CAEEL Unreviewed; 1522 AA.
AC P91350;
DT 01-MAY-1997, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 24-JAN-2024, entry version 145.
DE SubName: Full=Nuclear Pore complex Protein {ECO:0000313|EMBL:CCD66430.2};
GN Name=npp-6 {ECO:0000313|EMBL:CCD66430.2,
GN ECO:0000313|WormBase:F56A3.3a};
GN ORFNames=CELE_F56A3.3 {ECO:0000313|EMBL:CCD66430.2}, F56A3.3
GN {ECO:0000313|WormBase:F56A3.3a};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239 {ECO:0000313|EMBL:CCD66430.2, ECO:0000313|Proteomes:UP000001940};
RN [1] {ECO:0000313|EMBL:CCD66430.2, ECO:0000313|Proteomes:UP000001940}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2 {ECO:0000313|EMBL:CCD66430.2,
RC ECO:0000313|Proteomes:UP000001940};
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RA Sulson J.E., Waterston R.;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX284601; CCD66430.2; -; Genomic_DNA.
DR PIR; T29146; T29146.
DR RefSeq; NP_740844.1; NM_170857.3.
DR STRING; 6239.F56A3.3a.3; -.
DR EPD; P91350; -.
DR PaxDb; 6239-F56A3-3a-1; -.
DR PeptideAtlas; P91350; -.
DR EnsemblMetazoa; F56A3.3a.1; F56A3.3a.1; WBGene00003792.
DR EnsemblMetazoa; F56A3.3a.2; F56A3.3a.2; WBGene00003792.
DR UCSC; F56A3.3b; c. elegans.
DR AGR; WB:WBGene00003792; -.
DR WormBase; F56A3.3a; CE53750; WBGene00003792; npp-6.
DR eggNOG; KOG4521; Eukaryota.
DR HOGENOM; CLU_247500_0_0_1; -.
DR OrthoDB; 2879756at2759; -.
DR Proteomes; UP000001940; Chromosome I.
DR Bgee; WBGene00003792; Expressed in germ line (C elegans) and 4 other cell types or tissues.
DR ExpressionAtlas; P91350; baseline and differential.
DR GO; GO:0031965; C:nuclear membrane; IDA:UniProtKB.
DR GO; GO:0005643; C:nuclear pore; IDA:UniProtKB.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IBA:GO_Central.
DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:UniProtKB.
DR GO; GO:0043170; P:macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0071705; P:nitrogen compound transport; IEA:UniProt.
DR GO; GO:0006997; P:nucleus organization; IMP:UniProtKB.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR GO; GO:0110039; P:positive regulation of nematode male tail tip morphogenesis; IMP:UniProtKB.
DR GO; GO:0034501; P:protein localization to kinetochore; IMP:UniProtKB.
DR GO; GO:0090435; P:protein localization to nuclear envelope; IMP:UniProtKB.
DR InterPro; IPR021717; Nucleoporin_Nup160.
DR PANTHER; PTHR21286; NUCLEAR PORE COMPLEX PROTEIN NUP160; 1.
DR PANTHER; PTHR21286:SF0; NUCLEAR PORE COMPLEX PROTEIN NUP160; 1.
DR Pfam; PF11715; Nup160; 1.
PE 1: Evidence at protein level;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|EPD:P91350,
KW ECO:0007829|PeptideAtlas:P91350};
KW Reference proteome {ECO:0000313|Proteomes:UP000001940};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 1156..1211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1176..1211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1522 AA; 171564 MW; F6879ECB9C08C127 CRC64;
MELVYGSEIS FTDGFAIKPA RTFVVNTNAP LHSNGFDVQP SAGVATFPHC SNYGDRIFLW
RAIGQKLFIE ERSLLYSITD GSLCIDFTRT PIIPGTSITI FEEGVLCIVV PTASAIHRFY
ARLHSKGHDT FSILARIKED DDFRRFRTSH SLSTPGRPIR ASVTHHPSRN TISYCTAEGQ
LVIVTLGSYT ESSDKHEEFT MGEVGLLGKL LGGTDKRVSD ACVMKNLRPT SGVTRERKIS
VQSDIVFAVT RDGWVQAWNV ETKKQLPSTI DLNNYFASDG KSLNRDLESA DFEEEKSPME
PTETVYSIRA YSFDVDILLI VGCDLAVSGK SVGMRVHILK VSNDQIQHLQ MFETSMSVDE
RLVDLELIQN YFPSKESESL DETQDGELYN PLTAALFSLS ALFKSSSAKK TYSMKRISFA
IQWKKGRVFT DFDWHSVRQF TSPATTKEEP IGNTDEVEPA IERPYNLSAD SSIETLIDVV
FDTDIYPFDI VFRAVQIVSD NFRGTLGQVR NNNWPELSKL VDTYLTSVEF NRKFQQKTDR
SIRLRLNAPQ ESQKTALKDF WWALLRACEE LDFAARGAIS LAPIQFCGDL RIMAVVHRDR
MTFLGDNNTE FLEIISSENI PKQGNVEEKF RKLPNKHFID LIEEASKFAD RRVFLMNRER
ARLTNAKNGV AVVEDDNVEN AYDYDSDGRF INIKTALEGP IVKLAAAFVE ASTFDNSKPF
EDPHPQIFGG SFTQSVVSAN IRVSVESRVH FALTLQTLLN AITEKKSRAG APSFGDVEAL
SCELREIIRV YRELNEQLDI KIVQNGAKMS IGTWLTSDAE GLSMMKKEGG YGPHGYDEIR
ENDFNWFVGV TTEAAIRALL SSSEILVLPR RLVLQKQYKV LLTILNSYIS ETRALKPVIT
FYRGIAYSGT DHPVKALNSF QSCLDAFSEG NNALRKAVYF LLPKRFDVAQ GKDPVEELTA
SEYFLTVVRF LQEHNHAEEV CSVAVKAIEN LPIENESVQL ISNTLFNHLT NRREWFQSLK
LILRTTLRSE TRRASIRELL SLMLACGEWE AIATMKFGEH EQVVEDFLRD AACRQSPSEK
KHYFELLFAF YVARKDFRKG ACAMYEYARH IESTTCMTPE LLRRKRDCLA VVLNLQSVLG
MEPDDDRAIY DDATDTNLVF PEPSDDEDEL ITESDSSGEN GKLPSGNKDS GSGTGNNSSP
DNSNGTSSSG TGVDLVALKA RQMAYALGSD DMDTDDTEDD MKGGSIPLFK RRKLLVLSEK
DIRDELVLCS ARVGLLSSDQ FKGVPPTDLN ELFSLLVDNQ HFDEAFDIAR QFNLDSHRLF
FTMTREAIMI DALRDDLNIE MAATHQAGWV RLNRRHCAAV ATAEEHWSVV RGLVDAAQAE
WPGDSRPLRG STEAFLSFKL NVPVWLHSVF ENNDANDYLR CLVDYESYSI ALQVLSDIVE
QETLQASQSN ARTWLPYGII DELMIRSADY IRKMSLKSPE DQVVAAEVAN LRKSADQKML
IYFRKVADFE QAQKMSSRFF DK
//
