ID LPRB_MYCTO Reviewed; 185 AA.
AC P9WK52; L0T7T1; Q11045;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Putative lipoprotein LprB;
DE Flags: Precursor;
GN Name=lprB; OrderedLocusNames=MT1312;
OS Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83331;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CDC 1551 / Oshkosh;
RX PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT laboratory strains.";
RL J. Bacteriol. 184:5479-5490(2002).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK45572.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE000516; AAK45572.1; ALT_INIT; Genomic_DNA.
DR PIR; B70755; B70755.
DR RefSeq; WP_003901123.1; NZ_KK341227.1.
DR AlphaFoldDB; P9WK52; -.
DR KEGG; mtc:MT1312; -.
DR PATRIC; fig|83331.31.peg.1417; -.
DR HOGENOM; CLU_129265_0_0_11; -.
DR Proteomes; UP000001020; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR024520; DUF3558.
DR Pfam; PF12079; DUF3558; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 25..185
FT /note="Putative lipoprotein LprB"
FT /id="PRO_0000427714"
FT REGION 26..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 25
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 25
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 185 AA; 19739 MW; B412D6C748229453 CRC64;
MRRKVRRLTL AVSALVALFP AVAGCSDSGD NKPGATIPST PANAEGRHGP FFPQCGGVSD
QTVTELTRVT GLVNTAKNSV GCQWLAGGGI LGPHFSFSWY RGSPIGRERK TEELSRASVE
DINIDGHSGF IAIGNEPSLG DSLCEVGIQF SDDFIEWSVS FSQKPFPLPC DIAKELTRQS
IANSK
//
