ID PFDB_ARCFU Reviewed; 116 AA.
AC O29115;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE RecName: Full=Prefoldin subunit beta;
DE AltName: Full=GimC subunit beta;
GN Name=pfdB; OrderedLocusNames=AF_1150;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
CC -!- FUNCTION: Molecular chaperone capable of stabilizing a range of
CC proteins. Seems to fulfill an ATP-independent, HSP70-like function in
CC archaeal de novo protein folding (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Heterohexamer of two alpha and four beta subunits.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000305}.
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DR EMBL; AE000782; AAB90093.1; -; Genomic_DNA.
DR PIR; E69393; E69393.
DR RefSeq; WP_010878647.1; NC_000917.1.
DR AlphaFoldDB; O29115; -.
DR SMR; O29115; -.
DR STRING; 224325.AF_1150; -.
DR PaxDb; 224325-AF_1150; -.
DR EnsemblBacteria; AAB90093; AAB90093; AF_1150.
DR GeneID; 24794757; -.
DR KEGG; afu:AF_1150; -.
DR eggNOG; arCOG01342; Archaea.
DR HOGENOM; CLU_131909_1_1_2; -.
DR OrthoDB; 204796at2157; -.
DR PhylomeDB; O29115; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016272; C:prefoldin complex; IEA:UniProtKB-UniRule.
DR GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR CDD; cd00632; Prefoldin_beta; 1.
DR Gene3D; 1.10.287.370; -; 1.
DR HAMAP; MF_00307; PfdB; 1.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR012713; PfdB.
DR InterPro; IPR009053; Prefoldin.
DR NCBIfam; TIGR02338; gimC_beta; 1.
DR PANTHER; PTHR20903:SF0; PREFOLDIN SUBUNIT 1; 1.
DR PANTHER; PTHR20903; PREFOLDIN SUBUNIT 1-RELATED; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..116
FT /note="Prefoldin subunit beta"
FT /id="PRO_0000124857"
SQ SEQUENCE 116 AA; 13464 MW; 003EF50270BA751E CRC64;
MGELPPQVQN LVAQLQQLQQ QLQAVITQRA QVEALLRDTE QALEELQKVD DETPVYKAVG
NILVKEKKED VIKELTEKKE TYEIRIKTLQ RQEEKLRERF AETQQKLQNL LSPQAG
//
