ID PFDB_METPE Reviewed; 121 AA.
AC B8GDQ7;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE RecName: Full=Prefoldin subunit beta {ECO:0000255|HAMAP-Rule:MF_00307};
DE AltName: Full=GimC subunit beta {ECO:0000255|HAMAP-Rule:MF_00307};
GN Name=pfdB {ECO:0000255|HAMAP-Rule:MF_00307}; OrderedLocusNames=Mpal_2110;
OS Methanosphaerula palustris (strain ATCC BAA-1556 / DSM 19958 / E1-9c).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanoregulaceae; Methanosphaerula.
OX NCBI_TaxID=521011;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1556 / DSM 19958 / E1-9c;
RX PubMed=26543115; DOI=10.1128/genomea.01280-15;
RA Cadillo-Quiroz H., Browne P., Kyrpides N., Woyke T., Goodwin L., Detter C.,
RA Yavitt J.B., Zinder S.H.;
RT "Complete Genome Sequence of Methanosphaerula palustris E1-9CT, a
RT Hydrogenotrophic Methanogen Isolated from a Minerotrophic Fen Peatland.";
RL Genome Announc. 3:0-0(2015).
CC -!- FUNCTION: Molecular chaperone capable of stabilizing a range of
CC proteins. Seems to fulfill an ATP-independent, HSP70-like function in
CC archaeal de novo protein folding. {ECO:0000255|HAMAP-Rule:MF_00307}.
CC -!- SUBUNIT: Heterohexamer of two alpha and four beta subunits.
CC {ECO:0000255|HAMAP-Rule:MF_00307}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00307}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000255|HAMAP-Rule:MF_00307}.
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DR EMBL; CP001338; ACL17408.1; -; Genomic_DNA.
DR RefSeq; WP_012618727.1; NC_011832.1.
DR AlphaFoldDB; B8GDQ7; -.
DR SMR; B8GDQ7; -.
DR STRING; 521011.Mpal_2110; -.
DR GeneID; 7271588; -.
DR KEGG; mpl:Mpal_2110; -.
DR eggNOG; arCOG01342; Archaea.
DR HOGENOM; CLU_131909_0_0_2; -.
DR OrthoDB; 107608at2157; -.
DR Proteomes; UP000002457; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016272; C:prefoldin complex; IEA:UniProtKB-UniRule.
DR GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006457; P:protein folding; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.287.370; -; 1.
DR HAMAP; MF_00307; PfdB; 1.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR012713; PfdB.
DR InterPro; IPR009053; Prefoldin.
DR NCBIfam; TIGR02338; gimC_beta; 1.
DR PANTHER; PTHR20903:SF0; PREFOLDIN SUBUNIT 1; 1.
DR PANTHER; PTHR20903; PREFOLDIN SUBUNIT 1-RELATED; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 3: Inferred from homology;
KW Chaperone; Cytoplasm; Reference proteome.
FT CHAIN 1..121
FT /note="Prefoldin subunit beta"
FT /id="PRO_1000132878"
SQ SEQUENCE 121 AA; 13879 MW; CF038A80E064527C CRC64;
MSAISPKIQN QIAMLQQVQQ QMQTIMSQKT QYEMEIRENR RAEEELNDVP QESAVFMNVG
TVMMQKPKEK VIASLQEKAE SLELRVKSLE KQEKMMQAKF EQLQAQVKEA LEGGNRPPNA
A
//
