ID PSIG_DICDI Reviewed; 706 AA.
AC Q557E9; Q86HZ1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-MAY-2006, sequence version 1.
DT 24-JAN-2024, entry version 83.
DE RecName: Full=Protein psiG;
DE Flags: Precursor;
GN Name=psiG-1; ORFNames=DDB_G0273389;
GN and
GN Name=psiG-2; ORFNames=DDB_G0273605;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=12097910; DOI=10.1038/nature00847;
RA Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA Noegel A.A.;
RT "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL Nature 418:79-85(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the prespore-cell-inducing factor family.
CC {ECO:0000305}.
CC -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC AX4. These strains contain a duplication of a segment of 750 kb of
CC chromosome 2 compared to the corresponding sequence in strain AX2.
CC {ECO:0000305}.
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DR EMBL; AAFI02000011; EAL70493.1; -; Genomic_DNA.
DR EMBL; AAFI02000009; EAL70912.1; -; Genomic_DNA.
DR RefSeq; XP_644419.1; XM_639327.1.
DR RefSeq; XP_644831.1; XM_639739.1.
DR AlphaFoldDB; Q557E9; -.
DR GlyCosmos; Q557E9; 8 sites, No reported glycans.
DR PaxDb; 44689-DDB0232399; -.
DR EnsemblProtists; EAL70493; EAL70493; DDB_G0273605.
DR EnsemblProtists; EAL70912; EAL70912; DDB_G0273389.
DR GeneID; 8618933; -.
DR GeneID; 8619044; -.
DR KEGG; ddi:DDB_G0273389; -.
DR KEGG; ddi:DDB_G0273605; -.
DR dictyBase; DDB_G0273389; psiG-1.
DR dictyBase; DDB_G0273605; psiG-2.
DR eggNOG; ENOG502RFD8; Eukaryota.
DR HOGENOM; CLU_024170_0_0_1; -.
DR InParanoid; Q557E9; -.
DR OMA; CERHTPY; -.
DR PhylomeDB; Q557E9; -.
DR PRO; PR:Q557E9; -.
DR Proteomes; UP000002195; Chromosome 2.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011874; Fibro_Slime.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR InterPro; IPR001673; S_mold_repeat.
DR NCBIfam; TIGR02148; Fibro_Slime; 1.
DR PANTHER; PTHR31137; PROTEIN PSIB-RELATED-RELATED; 1.
DR PANTHER; PTHR31137:SF2; PROTEIN PSIG; 1.
DR Pfam; PF00526; Dicty_CTDC; 3.
DR Pfam; PF07691; PA14; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..706
FT /note="Protein psiG"
FT /id="PRO_0000327550"
FT TOPO_DOM 24..644
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 645..665
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 666..706
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 109..253
FT /note="PA14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01164"
FT REGION 687..706
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 95
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 107
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 212
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 296
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 429
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 521
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 532
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 616
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 706 AA; 76874 MW; 822BC0E933805A3F CRC64;
MKIILTLLII LFSLNKNLNF VSSEVTKSRI CSIFDQLPKL NSDFEPDYGD ISVGMIKNVL
EGDSPTLASN DPNFKPFVNG KLKNLNLFPT WFNKNHTQNV MLLKKLNLTL DKSSNIYSFV
KDDFFPIDYQ GWDVDESNRI YYGGRIFTAY HNFHYCLKIN SVFFYQGTET FKFEGDDDVW
VFIDKKLVLD LGGLHPARRG TVDLTKLGLQ VNKTYSFDFF YCERHTPYSK MKIQTDIQAF
CAWSDYCGVC QGDGSTCCNK DLDCDDDDPC TIDSCPLPNL PIPGGDKISK YCRHTNITCT
QPSNNKCVIT GCSKDTNGKC EVIGNLECAD KSKYCMTLTG CDPKLGCQYK SNCIGPCLTG
ECNNGKCTSM DADYCSNELG EDPCKIYSCN AKNGGCMATP KCTSPSSSNP CVIPTCSADK
GVCGTYTQNS TECNCNCKLN PCQKNNCDQS VNPPVCSPLP IDTIDDGNPC TIDICDKITG
SVKHTPMECS GCTKCNNGKC IPIESNCDDG NLCTIDQCMN NGSCIHTPLS CNITNPCMDY
TCNADIGCVG VPKICPNKGN CLIGYCDAGE CKLKDRICDS PSFCQISQCS DVTGCIVFDK
VCIPSNPKCE TGVCINATST EPGRCESVDF DPKPFVCKPA AIISTSVIVG VSVAAAVVAI
AIVVASKKGY DAWAASNNNS LASLTSNPLY ENPTGNGDNP MYQPNS
//
