ID PSIP_DICDI Reviewed; 756 AA.
AC Q54VS2;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE RecName: Full=Protein psiP;
DE Flags: Precursor;
GN Name=psiP; ORFNames=DDB_G0280171;
OS Dictyostelium discoideum (Social amoeba).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the prespore-cell-inducing factor family.
CC {ECO:0000305}.
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DR EMBL; AAFI02000035; EAL67312.1; -; Genomic_DNA.
DR RefSeq; XP_641283.1; XM_636191.1.
DR AlphaFoldDB; Q54VS2; -.
DR GlyCosmos; Q54VS2; 5 sites, No reported glycans.
DR PaxDb; 44689-DDB0232405; -.
DR EnsemblProtists; EAL67312; EAL67312; DDB_G0280171.
DR GeneID; 8622415; -.
DR KEGG; ddi:DDB_G0280171; -.
DR dictyBase; DDB_G0280171; psiP.
DR HOGENOM; CLU_024170_0_0_1; -.
DR InParanoid; Q54VS2; -.
DR OMA; DEICIHE; -.
DR PhylomeDB; Q54VS2; -.
DR PRO; PR:Q54VS2; -.
DR Proteomes; UP000002195; Chromosome 3.
DR GO; GO:0005576; C:extracellular region; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR011874; Fibro_Slime.
DR InterPro; IPR037524; PA14/GLEYA.
DR InterPro; IPR011658; PA14_dom.
DR NCBIfam; TIGR02148; Fibro_Slime; 1.
DR PANTHER; PTHR31137; PROTEIN PSIB-RELATED-RELATED; 1.
DR PANTHER; PTHR31137:SF29; PROTEIN PSIK-RELATED; 1.
DR Pfam; PF07691; PA14; 1.
DR SMART; SM00758; PA14; 1.
DR PROSITE; PS51820; PA14; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Membrane; Reference proteome; Signal; Transmembrane;
KW Transmembrane helix.
FT SIGNAL 1..23
FT /evidence="ECO:0000255"
FT CHAIN 24..756
FT /note="Protein psiP"
FT /id="PRO_0000327551"
FT TOPO_DOM 24..692
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 693..713
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 714..756
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 126..281
FT /note="PA14"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01164"
FT REGION 730..756
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 82
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 359
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 483
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 564
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 663
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 756 AA; 82455 MW; 4EBA177ECF4994C0 CRC64;
MFIQRTFLKV LTLLSIVTVL VHGQTQPKDK ITLKAVIYDQ HKFYNPNFQP KNEGEFVLTK
GIVKSDIDQE KRIPVLNSMD ANDSINKKAR ISWPDGFKYF FVDNQAGDSK SAKSGKNLPI
QRDIELNWNG EAYEYSNSNY FPINGQGFND VSYPVPRGYV PISGESWTSM STSTSLKGNN
YNFCLKLNSK FTYNGNEVFK FTGDDDVWVY INNKLVVDIG GIHSQVSASV DVTKLGLTVG
TIYNFDFFYC ERKTSESNIK IQTTIETYCA YVDYCGVCEG DGSTCCNPAT TCNDGKRCTN
DFCPDPKSPL AGKDISKYCD HIPVKTCSSK DTLCKQYTCS DDLKGDMCVI KNTVTCPGNQ
TNCEASGYCD DKFGCINPSK CTDYIGQCFS GKCVNGECAK VTADDCEKII GGVCRSDYVC
EPGLGCKSSE RCRQGSDICD LVTCDPKATD ESKRCITTVL TDEECRCCEY DTLRFCEQAA
CSNKTGLCQP IPKNVDDGNL CTIDACNEDE KTITHVQVTC GGCETCSYAT GKCEPDSSLC
NDNNICTIDI CVHEGILDGL PQGNCSNTPV DCGANDEDKC KTWSCDPTKG GCQSTPVVCE
DKGKCLVGTC QPSTGQCEYS DRVCDNGGAF CVIGQCDQRL GCLVFDRVCS SDNSRCEEGV
CVNGTESEEG HCKSVKYDPL PFNCNTGAVV STAVIAGSTV AGAVALGIFL YGGKKGYDYW
KDSRNISMGS SNSNPLYEEQ QTGRGVNPMY DDPAAN
//
