ID PUB26_ARATH Reviewed; 421 AA.
AC Q9FXA4; Q8GXA0;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 24-JAN-2024, entry version 131.
DE RecName: Full=U-box domain-containing protein 26;
DE EC=2.3.2.27;
DE AltName: Full=Plant U-box protein 26;
DE AltName: Full=RING-type E3 ubiquitin transferase PUB26 {ECO:0000305};
GN Name=PUB26; OrderedLocusNames=At1g49780; ORFNames=F14J22.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY ORGANIZATION, AND NOMENCLATURE.
RX PubMed=11495788; DOI=10.1016/s1360-1385(01)01960-4;
RA Azevedo C., Santos-Rosa M.J., Shirasu K.;
RT "The U-box protein family in plants.";
RL Trends Plant Sci. 6:354-358(2001).
RN [6]
RP GENE FAMILY ORGANIZATION.
RX PubMed=14657406; DOI=10.1104/pp.103.029553;
RA Mudgil Y., Shiu S.-H., Stone S.L., Salt J.N., Goring D.R.;
RT "A large complement of the predicted Arabidopsis ARM repeat proteins are
RT members of the U-box E3 ubiquitin ligase family.";
RL Plant Physiol. 134:59-66(2004).
CC -!- FUNCTION: Functions as an E3 ubiquitin ligase. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27;
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC011807; AAG13057.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE32475.1; -; Genomic_DNA.
DR EMBL; AK118346; BAC42960.1; -; mRNA.
DR EMBL; BT029013; ABI93922.1; -; mRNA.
DR PIR; E96534; E96534.
DR RefSeq; NP_175400.1; NM_103865.4.
DR AlphaFoldDB; Q9FXA4; -.
DR SMR; Q9FXA4; -.
DR STRING; 3702.Q9FXA4; -.
DR PaxDb; 3702-AT1G49780-1; -.
DR ProteomicsDB; 226254; -.
DR EnsemblPlants; AT1G49780.1; AT1G49780.1; AT1G49780.
DR GeneID; 841401; -.
DR Gramene; AT1G49780.1; AT1G49780.1; AT1G49780.
DR KEGG; ath:AT1G49780; -.
DR Araport; AT1G49780; -.
DR TAIR; AT1G49780; PUB26.
DR eggNOG; ENOG502QRXY; Eukaryota.
DR HOGENOM; CLU_006348_1_1_1; -.
DR InParanoid; Q9FXA4; -.
DR OMA; DCIANSD; -.
DR OrthoDB; 5489991at2759; -.
DR PhylomeDB; Q9FXA4; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9FXA4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FXA4; baseline and differential.
DR Genevisible; Q9FXA4; AT.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IDA:TAIR.
DR GO; GO:0098542; P:defense response to other organism; IMP:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IDA:TAIR.
DR CDD; cd16664; RING-Ubox_PUB; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR045185; PUB22/23/24-like.
DR InterPro; IPR045210; RING-Ubox_PUB.
DR InterPro; IPR003613; Ubox_domain.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR22849:SF112; U-BOX DOMAIN-CONTAINING PROTEIN 26; 1.
DR PANTHER; PTHR22849; WDSAM1 PROTEIN; 1.
DR Pfam; PF04564; U-box; 1.
DR SMART; SM00504; Ubox; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51698; U_BOX; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Transferase; Ubl conjugation pathway.
FT CHAIN 1..421
FT /note="U-box domain-containing protein 26"
FT /id="PRO_0000322170"
FT DOMAIN 13..87
FT /note="U-box"
FT CONFLICT 151
FT /note="R -> G (in Ref. 3; BAC42960)"
FT /evidence="ECO:0000305"
FT CONFLICT 286
FT /note="A -> V (in Ref. 3; BAC42960)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 421 AA; 45963 MW; 59D2A867E9AA1C9A CRC64;
MPGNLEPLDL GIQIPYHFRC PISLDLMSDP VTISTGQTYD RTSIDSWIAM GNTTCPVTRV
ALSDFTLIPN HTLRRLIQEW CVANRSNGVE RIPTPKQPAD PISVRSLLSQ ASAITGTHVS
VRSRAAAIRR LRGLARDSEK NRVLIAGHNA REILVRILFA DIETTSLSSE LVSESLALLV
LLHMTETECE AVASDPSRVG FMTRLLFDSS IEIRVNAAAL IEMVLTGAKS MDLKLIISGS
DSIFEGVLDL LKNPISSRRA LKIGIKAIFA LCLVKQTRHL AISAGAPGIL IDRLAADFDR
CDTERGLATV ELLCRLPEGC AAFGEHALTV PLMVKTILRV SDRATEYAAG ALLALCTAEE
RCRDEAAAAG LVTQLLLLVQ SDCTERAKRK AQMLLKLLRD SWPDDSTVHS DDFNRSEVAP
F
//
