GenomeNet

Database: UniProt
Entry: Q03302
LinkDB: Q03302
Original site: Q03302 
ID   SODM_HALMA              Reviewed;         203 AA.
AC   Q03302; Q5V3T9;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 2.
DT   16-JAN-2019, entry version 104.
DE   RecName: Full=Superoxide dismutase [Mn];
DE            EC=1.15.1.1;
GN   Name=sod; Synonyms=sodA; OrderedLocusNames=rrnAC0831;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria;
OC   Halobacteriales; Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8449865; DOI=10.1128/jb.175.6.1561-1571.1993;
RA   Joshi P.B., Dennis P.P.;
RT   "Characterization of paralogous and orthologous members of the
RT   superoxide dismutase gene family from genera of the halophilic
RT   archaebacteria.";
RL   J. Bacteriol. 175:1561-1571(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G.,
RA   Deutsch E.W., Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P.,
RA   Date S.V., Marcotte E., Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from
RT   the Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Destroys superoxide anion radicals which are normally
CC       produced within the cells and which are toxic to biological
CC       systems.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + 2 superoxide = H2O2 + O2; Xref=Rhea:RHEA:20696,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:18421; EC=1.15.1.1;
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
CC       Note=Binds 1 Mn(2+) ion per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the iron/manganese superoxide dismutase
CC       family. {ECO:0000305}.
DR   EMBL; M97485; AAA73374.1; -; Genomic_DNA.
DR   EMBL; AY596297; AAV45813.1; -; Genomic_DNA.
DR   PIR; T50044; T50044.
DR   RefSeq; WP_004961502.1; NC_006396.1.
DR   ProteinModelPortal; Q03302; -.
DR   SMR; Q03302; -.
DR   STRING; 272569.rrnAC0831; -.
DR   EnsemblBacteria; AAV45813; AAV45813; rrnAC0831.
DR   GeneID; 3129299; -.
DR   KEGG; hma:rrnAC0831; -.
DR   PATRIC; fig|272569.17.peg.1569; -.
DR   eggNOG; arCOG04147; Archaea.
DR   eggNOG; COG0605; LUCA.
DR   HOGENOM; HOG000013583; -.
DR   KO; K04564; -.
DR   OMA; YEGWKGE; -.
DR   Proteomes; UP000001169; Chromosome I.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.287.990; -; 1.
DR   Gene3D; 2.40.500.20; -; 1.
DR   InterPro; IPR001189; Mn/Fe_SOD.
DR   InterPro; IPR019833; Mn/Fe_SOD_BS.
DR   InterPro; IPR019832; Mn/Fe_SOD_C.
DR   InterPro; IPR019831; Mn/Fe_SOD_N.
DR   InterPro; IPR036324; Mn/Fe_SOD_N_sf.
DR   InterPro; IPR036314; SOD_C_sf.
DR   Pfam; PF02777; Sod_Fe_C; 1.
DR   Pfam; PF00081; Sod_Fe_N; 1.
DR   PIRSF; PIRSF000349; SODismutase; 1.
DR   PRINTS; PR01703; MNSODISMTASE.
DR   SUPFAM; SSF46609; SSF46609; 1.
DR   SUPFAM; SSF54719; SSF54719; 1.
DR   PROSITE; PS00088; SOD_MN; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Manganese; Metal-binding; Oxidoreductase;
KW   Reference proteome.
FT   CHAIN         1    203       Superoxide dismutase [Mn].
FT                                /FTId=PRO_0000160113.
FT   METAL        31     31       Manganese. {ECO:0000250}.
FT   METAL        79     79       Manganese. {ECO:0000250}.
FT   METAL       161    161       Manganese. {ECO:0000250}.
FT   METAL       165    165       Manganese. {ECO:0000250}.
FT   CONFLICT     66     67       MG -> WV (in Ref. 1; AAA73374).
FT                                {ECO:0000305}.
FT   CONFLICT     76     77       HY -> QD (in Ref. 1; AAA73374).
FT                                {ECO:0000305}.
FT   CONFLICT    134    134       V -> C (in Ref. 1; AAA73374).
FT                                {ECO:0000305}.
SQ   SEQUENCE   203 AA;  22726 MW;  A20197A10C2948E0 CRC64;
     MSEHSNPELP PLPYDYDALE PHISEQVLTW HHDTHHQGYV NGLESAEETL AENRDAGDFG
     SSAAAMGNVT HNGCGHYLHT LFWENMDPNG GGEPEGELLD RIEEDFGSYE GWKGEFEAAA
     SAAGGWALLV YDPVAKQLRN VPVDKHDQGA LWGSHPILAL DVWEHSYYYD YGPARGDFID
     AFFEVVDWDK AAEEYEKSVS HFE
//
DBGET integrated database retrieval system