ID Q03BH4_LACP3 Unreviewed; 462 AA.
AC Q03BH4;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE RecName: Full=Branched-chain amino acid transport system carrier protein {ECO:0000256|RuleBase:RU362122};
GN OrderedLocusNames=LSEI_0604 {ECO:0000313|EMBL:ABJ69448.1};
OS Lacticaseibacillus paracasei (strain ATCC 334 / BCRC 17002 / CCUG 31169 /
OS CIP 107868 / KCTC 3260 / NRRL B-441) (Lactobacillus paracasei).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=321967 {ECO:0000313|EMBL:ABJ69448.1, ECO:0000313|Proteomes:UP000001651};
RN [1] {ECO:0000313|EMBL:ABJ69448.1, ECO:0000313|Proteomes:UP000001651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 334 / BCRC 17002 / CCUG 31169 / CIP 107868 / KCTC 3260 /
RC NRRL B-441 {ECO:0000313|Proteomes:UP000001651};
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA Kozyavkin S., Weimer B., Mills D.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- FUNCTION: Component of the transport system for branched-chain amino
CC acids. {ECO:0000256|RuleBase:RU362122}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU362122};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU362122}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the branched chain amino acid transporter
CC family. {ECO:0000256|ARBA:ARBA00008540, ECO:0000256|RuleBase:RU362122}.
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DR EMBL; CP000423; ABJ69448.1; -; Genomic_DNA.
DR RefSeq; WP_003573816.1; NC_008526.1.
DR RefSeq; YP_805890.1; NC_008526.1.
DR AlphaFoldDB; Q03BH4; -.
DR PaxDb; 321967-LSEI_0604; -.
DR KEGG; lca:LSEI_0604; -.
DR PATRIC; fig|321967.11.peg.606; -.
DR HOGENOM; CLU_036807_0_1_9; -.
DR Proteomes; UP000001651; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015658; F:branched-chain amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004685; Brnchd-chn_aa_trnsp_Livcs.
DR NCBIfam; TIGR00796; livcs; 1.
DR PANTHER; PTHR30588; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR PANTHER; PTHR30588:SF0; BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM 2 CARRIER PROTEIN; 1.
DR Pfam; PF05525; Branch_AA_trans; 1.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|ARBA:ARBA00022970,
KW ECO:0000256|RuleBase:RU362122};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362122};
KW Reference proteome {ECO:0000313|Proteomes:UP000001651};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362122};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362122};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362122}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 44..69
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 81..102
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 122..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 156..173
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 207..225
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 246..265
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 285..311
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 323..340
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 346..366
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 378..402
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
FT TRANSMEM 422..446
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362122"
SQ SEQUENCE 462 AA; 49444 MW; 178E602BBF385186 CRC64;
MELSEKKLKT RDYVVIASLL FGLFFGAGNL IFPLHLGQLA GANWFPAMLG FLVTAVALPL
LGVLAIAATH AEGVYDIGRP LGRFFALAFM VLIHATIGPM FGTPRTATVS FTTGVLPMLP
KAWAQVGLLV FSALFFAAAF FLSYKERKIT TAVGKILNPV FLVLLFFVFF IGFSHPMGNP
ATQTVTAAYK NASFMNGFLQ GYNTMDALAA LAFGVTVVTA VRGLGLKNDD DVAKSTAKAG
VMATSWIGLI YVALILLGSM SLAHFKLSPE GGTAFNQVVT YYFGAAGHAV LATLLTLTCL
TTAVGLVAAF AQDFHRHFPK VSYRVWLALT SFLSFLTANF GLEQIIAWSV PMLMFLYPFS
MVLILLSVFG KAFHHDPLVY RFVVGFTAVP AVLDMFAAFP AFVSQSALGL ALHSFQLHFL
PFAGMGLGWL VPAGVGLAVG LVAHAVKVRK AVAVAKLGAE EN
//
