ID Q03GQ2_PEDPA Unreviewed; 492 AA.
AC Q03GQ2;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Type II restriction endonuclease, MutH family {ECO:0000313|EMBL:ABJ67620.1};
GN OrderedLocusNames=PEPE_0531 {ECO:0000313|EMBL:ABJ67620.1};
OS Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 /
OS 183-1w).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Pediococcus.
OX NCBI_TaxID=278197 {ECO:0000313|EMBL:ABJ67620.1, ECO:0000313|Proteomes:UP000000773};
RN [1] {ECO:0000313|EMBL:ABJ67620.1, ECO:0000313|Proteomes:UP000000773}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w
RC {ECO:0000313|Proteomes:UP000000773};
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA Kozyavkin S., Weimer B., Mills D.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
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DR EMBL; CP000422; ABJ67620.1; -; Genomic_DNA.
DR RefSeq; WP_011673121.1; NC_008525.1.
DR AlphaFoldDB; Q03GQ2; -.
DR STRING; 278197.PEPE_0531; -.
DR REBASE; 13812; PpeAORF532P.
DR GeneID; 33061361; -.
DR KEGG; ppe:PEPE_0531; -.
DR eggNOG; COG3066; Bacteria.
DR HOGENOM; CLU_514675_0_0_9; -.
DR OrthoDB; 3188707at2; -.
DR Proteomes; UP000000773; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR CDD; cd22355; Sau3AI_C; 1.
DR CDD; cd22356; Sau3AI_N-like; 1.
DR Gene3D; 3.40.600.10; DNA mismatch repair MutH/Restriction endonuclease, type II; 2.
DR InterPro; IPR011337; DNA_rep_MutH/RE_typeII_Sau3AI.
DR InterPro; IPR037057; DNA_rep_MutH/T2_RE_sf.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR Pfam; PF02976; MutH; 1.
DR SMART; SM00927; MutH; 1.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 2.
PE 4: Predicted;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759, ECO:0000313|EMBL:ABJ67620.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722}.
FT DOMAIN 56..167
FT /note="DNA mismatch repair MutH/Type II restriction enzyme
FT Sau3AI"
FT /evidence="ECO:0000259|SMART:SM00927"
SQ SEQUENCE 492 AA; 56852 MW; AF393159D2F476C6 CRC64;
MPSHEYTKTQ LIGLLERAVN KTLGEVDTAH VFDKTKNNKK ITGIAGDVIE NSVLGYPSDS
YQSPDLCVDG VDIELKTTGI KVAKKKSKSH LFEAKEPMSI TAVSPEKITT EEFESSNFWH
KLERMLLVYY FYDSDVTVTA AEYANFLIKG YDFHEFSKED QETLKNDWKI VQQFIQNLQN
GYGEEASSQY PRISSEIRSQ LMMIDTAPKW PHRPRFRLKR ATVTTMVQEY FGKKLENLSQ
SYSSFDALDQ ELHKFTKQYH GMTIRELIKE LSISIKLNKQ DDAPKSVTEQ IVTHMFGAKS
KKINSIEDFK KLGLIAKTIT QTAKGTRTED VKISRIDFEE FKPENDLFEE SLIYNYFNEQ
QFLCILFEEP NTSSKLLENR FLGFKRLSFP DEFINQDVKK TWQKIRYLVI HNKLVDVISY
DKNGHPRKNK KTNTIVSAPN FPKSSEGSVF VRGSSSDSCH KPLTINGIRM YSQYIWIKGS
TFLNMLNDTK FI
//
