ID Q03ZX2_LEUMM Unreviewed; 465 AA.
AC Q03ZX2;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 97.
DE SubName: Full=Fumarate reductase, flavoprotein subunit {ECO:0000313|EMBL:ABJ61250.1};
GN OrderedLocusNames=LEUM_0098 {ECO:0000313|EMBL:ABJ61250.1};
OS Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM
OS 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB
OS 8023 / NCTC 12954 / NRRL B-1118 / 37Y).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Leuconostoc.
OX NCBI_TaxID=203120 {ECO:0000313|EMBL:ABJ61250.1, ECO:0000313|Proteomes:UP000000362};
RN [1] {ECO:0000313|EMBL:ABJ61250.1, ECO:0000313|Proteomes:UP000000362}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO
RC 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y
RC {ECO:0000313|Proteomes:UP000000362};
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA Kozyavkin S., Weimer B., Mills D.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase 2 family.
CC FRD/SDH subfamily. {ECO:0000256|RuleBase:RU366062}.
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DR EMBL; CP000414; ABJ61250.1; -; Genomic_DNA.
DR RefSeq; WP_011679073.1; NC_008531.1.
DR AlphaFoldDB; Q03ZX2; -.
DR EnsemblBacteria; ABJ61250; ABJ61250; LEUM_0098.
DR GeneID; 61177422; -.
DR KEGG; lme:LEUM_0098; -.
DR eggNOG; COG1053; Bacteria.
DR HOGENOM; CLU_011398_4_5_9; -.
DR Proteomes; UP000000362; Chromosome.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.90.700.10; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
DR InterPro; IPR003953; FAD-binding_2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR010960; Flavocytochrome_c.
DR InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat_sf.
DR NCBIfam; TIGR01813; flavo_cyto_c; 1.
DR PANTHER; PTHR43400:SF7; FAD_BINDING_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43400; FUMARATE REDUCTASE; 1.
DR Pfam; PF00890; FAD_binding_2; 1.
DR PRINTS; PR00368; FADPNR.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF56425; Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|RuleBase:RU366062};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630,
KW ECO:0000256|RuleBase:RU366062};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU366062}.
FT DOMAIN 19..443
FT /note="FAD-dependent oxidoreductase 2 FAD binding"
FT /evidence="ECO:0000259|Pfam:PF00890"
SQ SEQUENCE 465 AA; 50054 MW; F203A78ECBE4DC95 CRC64;
MVKFNFSCTN IDNLKSSYDF VVIGSGATGM TAAIQAQELG LDVVIFEKLN SLGGNSMRAS
TGMNAVETMT QLKYQIIDSQ ESFYEETLKG GKGSNNKELL SYFVRHTESA IEWLSYHNIE
LNEIVSTGGM SKKRAHQPTG ATAIGGYLVK GLQQQLAEKR IPVFNQTKVL SLVKNDGHIS
GVEIEHPQAG KKIINAKTVL IASGGFAQNR AMMSVYAPDL LRLGTTNHPG ATGDGIKLAT
TAGGALVDMN KVQVHPTAQQ ETDHIYLIGE GLRGAGAILI NHLGKRFTNE MATRDQVTKA
IDDLHQDGAT LVFDQGICEA FKAADFYVAM GLAVSGNTIY ELAEKIGVNP NNLEKTVSGW
NMYQKAFEDI AFDRQTGMDR GIEKSPYYAI HIKPAVHYTM GGIKTNRLTE VLNEIGEAVP
GLFAAGEVAG GLHGDNRIGG NSIAETIVFG RQAGQQAAKH VLSLS
//
