ID Q04FW9_OENOB Unreviewed; 423 AA.
AC Q04FW9;
DT 14-NOV-2006, integrated into UniProtKB/TrEMBL.
DT 14-NOV-2006, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=D-alanyl-D-alanine carboxypeptidase {ECO:0000313|EMBL:ABJ56653.1};
GN OrderedLocusNames=OEOE_0719 {ECO:0000313|EMBL:ABJ56653.1};
OS Oenococcus oeni (strain ATCC BAA-331 / PSU-1).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Oenococcus.
OX NCBI_TaxID=203123 {ECO:0000313|EMBL:ABJ56653.1, ECO:0000313|Proteomes:UP000000774};
RN [1] {ECO:0000313|EMBL:ABJ56653.1, ECO:0000313|Proteomes:UP000000774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-331 / PSU-1 {ECO:0000313|Proteomes:UP000000774};
RX PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E.,
RA Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R.,
RA O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P.,
RA Kozyavkin S., Weimer B., Mills D.;
RT "Comparative genomics of the lactic acid bacteria.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC -!- SIMILARITY: Belongs to the peptidase S11 family.
CC {ECO:0000256|ARBA:ARBA00007164, ECO:0000256|RuleBase:RU004016}.
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DR EMBL; CP000411; ABJ56653.1; -; Genomic_DNA.
DR RefSeq; WP_011677542.1; NC_008528.1.
DR AlphaFoldDB; Q04FW9; -.
DR STRING; 203123.OEOE_0719; -.
DR KEGG; ooe:OEOE_0719; -.
DR PATRIC; fig|203123.7.peg.727; -.
DR eggNOG; COG1686; Bacteria.
DR HOGENOM; CLU_027070_8_2_9; -.
DR Proteomes; UP000000774; Chromosome.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR018044; Peptidase_S11.
DR InterPro; IPR001967; Peptidase_S11_N.
DR PANTHER; PTHR21581; D-ALANYL-D-ALANINE CARBOXYPEPTIDASE; 1.
DR PANTHER; PTHR21581:SF11; D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA; 1.
DR Pfam; PF00768; Peptidase_S11; 1.
DR PRINTS; PR00725; DADACBPTASE1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Carboxypeptidase {ECO:0000313|EMBL:ABJ56653.1};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Protease {ECO:0000313|EMBL:ABJ56653.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000774};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 33..282
FT /note="Peptidase S11 D-alanyl-D-alanine carboxypeptidase A
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00768"
FT ACT_SITE 65
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT ACT_SITE 68
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT ACT_SITE 129
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-1"
FT BINDING 253
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR618044-2"
SQ SEQUENCE 423 AA; 46053 MW; 5235C4BF74794BEA CRC64;
MQLKTFKQFI LSLFAFFTVF SINVLKVKAA IITPSIKAKG AIVIDEKTGQ ILASKNADKR
YPIASISKLL IAYLVEKRIK ENKISLNTKV KIPSGIVAIS QETTITNVPL SATRSYTIKE
LLEDALLPSG NGAAIALGAA ITGSVSKTET AMEKLLSSWN IKGVKIYSPA GLTNGEMGAY
KDKSASDDAE NKLSAKELAE VSRHLMLDFP SIRKITDKSS AVVSSTSGSS YTIENTNQLL
KNIKSPYKFT GIKTGSAESI GGNFIGETRI KGQKVITVVL GSGSMTDEST RFVQTVSMLS
QLNKASSIKK IAKSEGSAKL IAATGKNGKV KTINSYRYSL FVPKKKTSLV YSSIKVKKNI
SYPLSKGKMI GYDEVKTSSN LAKDFLYGKY LSVKVDSNER VKETNFIVRA WRQLFFSKSF
QTN
//
