ID   SYRM_RHIET              Reviewed;         336 AA.
AC   Q08812;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-MAY-2023, entry version 84.
DE   RecName: Full=HTH-type transcriptional regulator SyrM;
DE   AltName: Full=Symbiotic regulator;
GN   Name=syrM;
OS   Rhizobium etli.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=29449;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=CNPAF512;
RX   PubMed=8367305; DOI=10.1093/nar/21.16.3893;
RA   Michiels J., de Wilde P., Vanderleyden J.;
RT   "Sequence of the Rhizobium leguminosarum biovar phaseoli syrM gene.";
RL   Nucleic Acids Res. 21:3893-3893(1993).
CC   -!- FUNCTION: Acts in trans to stimulate nod gene expression via nodD3 and
CC       exo gene expression via SyrA.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Strain CNPAF512 was originally thought to originate from
CC       R.leguminosarum bv phaseoli. {ECO:0000305}.
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DR   EMBL; Z23013; CAA80556.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q08812; -.
DR   SMR; Q08812; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08467; PBP2_SyrM; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR037417; SyrM_PBP2.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30118; HTH-TYPE TRANSCRIPTIONAL REGULATOR LEUO-RELATED; 1.
DR   PANTHER; PTHR30118:SF15; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Nodulation; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..336
FT                   /note="HTH-type transcriptional regulator SyrM"
FT                   /id="PRO_0000105752"
FT   DOMAIN          41..98
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        58..77
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   336 AA;  37801 MW;  FACF9463A6A872BD CRC64;
     MNFMKRNVEK EVTDQLAYRR KMLQDWRGER LTGHQINLAS IDLNLLVALE ALLEYRNVTH
     AGQHIGRSQP AMSRALGRLR GLFNDDLLVR SSTGLIPTPQ GEHLAQRLPS ALRTIREMVT
     SRSVISKEWG RGATLAIPDH QALAVLPRLL PWLRERAPHL DTLACLPFDR AVRGLEQGDI
     DLAVGHIDVQ LPGYFRRSLY TDRFACLLRH GHPALAQEWT IDNFATLRHA AISTDSPDHF
     GPIYDHLPNL RADRSPILFS SVLTAAVVAS ATDLVLLVPR RVATQVSAML PLRVVDPPLE
     PAPYKVMLIW HERCHHDPQH KWLRKEVAAA LETGAD
//