ID Q088L6_SHEFN Unreviewed; 389 AA.
AC Q088L6;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=HemY domain protein {ECO:0000313|EMBL:ABI70299.1};
GN OrderedLocusNames=Sfri_0437 {ECO:0000313|EMBL:ABI70299.1};
OS Shewanella frigidimarina (strain NCIMB 400).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=318167 {ECO:0000313|EMBL:ABI70299.1, ECO:0000313|Proteomes:UP000000684};
RN [1] {ECO:0000313|EMBL:ABI70299.1, ECO:0000313|Proteomes:UP000000684}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 400 {ECO:0000313|EMBL:ABI70299.1,
RC ECO:0000313|Proteomes:UP000000684};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Fredrickson J.K., Kolker E., McCuel L.A., DiChristina T., Nealson K.H.,
RA Newman D., Tiedje J.M., Zhou J., Romine M.F., Culley D.E., Serres M.,
RA Chertkov O., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.;
RT "Complete sequence of Shewanella frigidimarina NCIMB 400.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in a late step of protoheme IX synthesis.
CC {ECO:0000256|ARBA:ARBA00002962}.
CC -!- PATHWAY: Porphyrin-containing compound metabolism; protoheme
CC biosynthesis. {ECO:0000256|ARBA:ARBA00004744}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}.
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DR EMBL; CP000447; ABI70299.1; -; Genomic_DNA.
DR RefSeq; WP_011635926.1; NC_008345.1.
DR AlphaFoldDB; Q088L6; -.
DR STRING; 318167.Sfri_0437; -.
DR KEGG; sfr:Sfri_0437; -.
DR eggNOG; COG3071; Bacteria.
DR HOGENOM; CLU_037501_2_1_6; -.
DR OrthoDB; 7067577at2; -.
DR UniPathway; UPA00252; -.
DR Proteomes; UP000000684; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042168; P:heme metabolic process; IEA:InterPro.
DR GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR005254; Heme_biosyn_assoc_TPR_pro.
DR InterPro; IPR010817; HemY_N.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00540; TPR_hemY_coli; 1.
DR Pfam; PF07219; HemY_N; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
PE 4: Predicted;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Porphyrin biosynthesis {ECO:0000256|ARBA:ARBA00023244};
KW Reference proteome {ECO:0000313|Proteomes:UP000000684};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 26..132
FT /note="HemY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF07219"
SQ SEQUENCE 389 AA; 43780 MW; 9F8AD9F9469E147F CRC64;
MIKTLVYVVL ILIGLCISPL IIGQSGYIYI AIGEYQIETS LVTGIVGLIV FYFALQLLEW
LIILLLNIVL SSRYLPEQWR RKAAKKHTLI GALALAEEDW PAAEKAMAKG AEKGEIPVLN
LFAAARAAHY QGDITARDHY LTQAEKNPIA KTAVYTSRTR YLMKQGELVK ARAILDKLNP
TSKSSSPVLK LAQELYLQQQ DWQALKLLLP ILKKRQLLAE TEFNQLNTKT NSILMINAAK
ISEAELTKCW HWLNKSERKE DELILAYARG LIQYGHKDQA LKLINKQLNA SPSAALFTAI
PDLITAQDQD IRKLLSKLET THENDADYQM CLAKLAIQSR ETKQAKTHWQ NVCRIAPTHQ
SWLALAQTQE QLGENSTAAH SYRNAANIL
//
