ID Q08CX3_XENTR Unreviewed; 637 AA.
AC Q08CX3; F6PX45; F6UFY1;
DT 31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 31-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Nef-associated factor 1 {ECO:0000313|EMBL:AAI24048.1};
DE SubName: Full=TNFAIP3-interacting protein 1 {ECO:0000313|Ensembl:ENSXETP00000034509, ECO:0000313|RefSeq:NP_001072703.1};
GN Name=tnip1 {ECO:0000313|EMBL:AAI24048.1,
GN ECO:0000313|Ensembl:ENSXETP00000034509,
GN ECO:0000313|RefSeq:NP_001072703.1,
GN ECO:0000313|Xenbase:XB-GENE-945173};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI24048.1};
RN [1] {ECO:0000313|RefSeq:NP_001072703.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=12454917; DOI=10.1002/dvdy.10174;
RA Klein S.L., Strausberg R.L., Wagner L., Pontius J., Clifton S.W.,
RA Richardson P.;
RT "Genetic and genomic tools for Xenopus research: The NIH Xenopus
RT initiative.";
RL Dev. Dyn. 225:384-391(2002).
RN [2] {ECO:0000313|EMBL:AAI24048.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=N6 {ECO:0000313|EMBL:AAI24048.1};
RC TISSUE=Oviduct {ECO:0000313|EMBL:AAI24048.1};
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSXETP00000034509}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000034509};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [4] {ECO:0000313|Ensembl:ENSXETP00000034509}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JUN-2011) to UniProtKB.
RN [5] {ECO:0000313|RefSeq:NP_001072703.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; BC124047; AAI24048.1; -; mRNA.
DR RefSeq; NP_001072703.1; NM_001079235.1.
DR STRING; 8364.ENSXETP00000030962; -.
DR PaxDb; 8364-ENSXETP00000034509; -.
DR PaxDb; 8364-ENSXETP00000061768; -.
DR DNASU; 780160; -.
DR Ensembl; ENSXETT00000034509; ENSXETP00000034509; ENSXETG00000015831.
DR GeneID; 780160; -.
DR KEGG; xtr:780160; -.
DR AGR; Xenbase:XB-GENE-945173; -.
DR CTD; 10318; -.
DR Xenbase; XB-GENE-945173; tnip1.
DR eggNOG; ENOG502QPYT; Eukaryota.
DR HOGENOM; CLU_033970_0_0_1; -.
DR OMA; KCEANGL; -.
DR OrthoDB; 4338840at2759; -.
DR TreeFam; TF351138; -.
DR Proteomes; UP000008143; Chromosome 3.
DR Bgee; ENSXETG00000015831; Expressed in testis and 19 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR Gene3D; 1.20.5.990; Nemo cc2-lz domain - 1d5 darpin complex; 1.
DR InterPro; IPR032419; CC2-LZ_dom.
DR PANTHER; PTHR31882:SF3; TNFAIP3-INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR31882; TNFAIP3-INTERACTING PROTEIN COILED COIL FAMILY MEMBER; 1.
DR Pfam; PF16516; CC2-LZ; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT DOMAIN 416..513
FT /note="NF-kappa-B essential modulator NEMO CC2-LZ"
FT /evidence="ECO:0000259|Pfam:PF16516"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 611..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 42..69
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 339..524
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 120..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..156
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 73252 MW; FBD0C72DB12911A5 CRC64;
MESKGPYRIY DPGGSEPSPS TNKGVQTLMK DNPALRESME GIRSLGELLE ESENEVYRLR
QKAEALVKDN KHLHSSSAMD SQPSFLEETV LGRKLSAGSE QAEGLQSPKM TDLDSDVHPK
SNQKTPPSGT SSEFEILNAY ETRKTPESRK LDPGPTLPQE DDNVQLHLQR METSLSMFAE
EPDRKSPIAH ISRLALDFSR LASKVHKNEQ KTAVLQTLCE QLRKENEDLR AKLEADWNQR
TQAEQALRYE NLELKKLILQ SDRGGGKGFH AGGGVDSAAQ EDAVKLENPG IQQVAKLMEK
PAVKDPSVSL LKKVKILEHQ RTELLEVNKQ WDQQFRSMKM QYEEKITSLR QKLSQASKAE
SEQEVEKDRK QRDFDRKLLL ARDKIEEKES QIQKLESEVR ELKQKNKFLH EQLSSTSKQR
EYQEREISRL NKALEEALNM QGSGPCSPSL IASLEDPRLP QREELQMQND ILKQQVKIFE
EDFQKERRDR ERMNEEKEEL KRQLELLQTQ LGQVNTQLRS CQEDLRREME SSRDAVRKQA
LGERYIVDPH MGHVCPPYQY PYSPPGLVYP AFEDWQIRYP PPVVHPEHSQ IQDLNNVPPP
AYPWRMATIL PRMQNSKNKK KEQDIAGSGT QNAPRQT
//
