ID Q0AWQ4_SYNWW Unreviewed; 989 AA.
AC Q0AWQ4;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Type III restriction system endonuclease {ECO:0000313|EMBL:ABI68850.1};
GN OrderedLocusNames=Swol_1547 {ECO:0000313|EMBL:ABI68850.1};
OS Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Syntrophomonadaceae;
OC Syntrophomonas.
OX NCBI_TaxID=335541 {ECO:0000313|EMBL:ABI68850.1, ECO:0000313|Proteomes:UP000001968};
RN [1] {ECO:0000313|Proteomes:UP000001968}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2245B / Goettingen {ECO:0000313|Proteomes:UP000001968};
RX PubMed=21966920; DOI=10.1111/j.1462-2920.2010.02237.x;
RA Sieber J.R., Sims D.R., Han C., Kim E., Lykidis A., Lapidus A.L.,
RA McDonnald E., Rohlin L., Culley D.E., Gunsalus R., McInerney M.J.;
RT "The genome of Syntrophomonas wolfei: new insights into syntrophic
RT metabolism and biohydrogen production.";
RL Environ. Microbiol. 12:2289-2301(2010).
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DR EMBL; CP000448; ABI68850.1; -; Genomic_DNA.
DR RefSeq; WP_011640949.1; NC_008346.1.
DR AlphaFoldDB; Q0AWQ4; -.
DR STRING; 335541.Swol_1547; -.
DR REBASE; 12315; SwoGORF1548P.
DR KEGG; swo:Swol_1547; -.
DR eggNOG; COG3587; Bacteria.
DR HOGENOM; CLU_011799_0_0_9; -.
DR OrthoDB; 9804145at2; -.
DR Proteomes; UP000001968; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0015668; F:type III site-specific deoxyribonuclease activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR045572; RE_endonuc_C.
DR Pfam; PF19778; RE_endonuc; 1.
DR Pfam; PF04851; ResIII; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:ABI68850.1};
KW Hydrolase {ECO:0000313|EMBL:ABI68850.1};
KW Nuclease {ECO:0000313|EMBL:ABI68850.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001968}.
FT DOMAIN 85..256
FT /note="Helicase/UvrB N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04851"
FT DOMAIN 875..981
FT /note="Type III restriction enzyme C-terminal endonuclease"
FT /evidence="ECO:0000259|Pfam:PF19778"
SQ SEQUENCE 989 AA; 113725 MW; 871EB5E6C3EBE928 CRC64;
MKLKFVSDQQ FQLDAVASIS DIFQGQAVKQ ANFSVASTMG SSAQGELGYQ TELGYANKLD
LLDDELLENI NRIQLRNGLP KSTDIQGRNF TVEMETGTGK TYVYIRTIYE LNKLYGFTKF
IIVVPSVAIR EGVNKSLEIM EEHFKSLYEG ANCDYFIYDS SKLGQLRTFA TSSNIQIMVI
NIDAFRKSFV DPNKPDKANI IHREHDRMNG RRPIEFIQQT NPIVIIDEPQ SVDRTDKAKE
AIASLNPLCT LRYSATHVET YNLMYCLGPV DAYQKKLVKE IVVDSIKEAG NFNRPYIRLV
SVKNSNGFQA VLELDIKNRS GVVQRKQKTV RVGQDLFDIS GEREIYSGYI INNIDCYPGN
EMVEFTNGSH LPLGMEMGNI SGDDIKRGQI SATIKHHLDR ELRLVPQGIK VLSLFFIDRV
DNYRIYDSNG NPQKGKYALM FEEEYSKLIK LPKYRTLFED HNYMLNDDPS MVHDGYFSID
KKGRIKDTRG NTLADHDTYN LIMKEKEKLL SFETPLRFIF SHSALKEGWD NPNVFQICTL
IEARETLTRR QKIGRGLRLC VNQEGERIFD PQINTLSVMA NESFAEFAEN LQSEMEAETG
VKFGFIEKHA FAGISYTDDS GKIENLGYEA SENLWGFLLE EDLIYTTGKV KLELKEQIAN
DTFQVPPEFE HVEQEIKQVI RQSLNKLPIR NHNNEVTAQL NKRVYLGPEF ESLWNRIKFR
TTYSVAMDIE KLVQECVDAI NRMPAIPKVR LIQESARIDI NQSGVSGELT SVKVLDQIDI
KHSLPDILRY LQDETRLTRR TIVRILIEAR RLEDFKNNPQ KFMEAVSDII KQRMKLMIAD
GIKYERVGNL EFYRQELFEM QELKGYLKSN AIKVEKSVYD YLILDSNTEK EFAQMLEQDD
EVKVYTKLPP KFVIETPIGN YNPDWAVLVD KDGTEKLYFV VETKGSTDSG QLRLFENYKI
ECGKKHFAAL ETGVTYEVAK DYAEWKLGI
//
