ID Q0BQM9_GRABC Unreviewed; 874 AA.
AC Q0BQM9;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 75.
DE SubName: Full=Acriflavin resistance plasma membrane protein {ECO:0000313|EMBL:ABI62873.1};
GN OrderedLocusNames=GbCGDNIH1_1975 {ECO:0000313|EMBL:ABI62873.1};
OS Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Granulibacter.
OX NCBI_TaxID=391165 {ECO:0000313|EMBL:ABI62873.1, ECO:0000313|Proteomes:UP000001963};
RN [1] {ECO:0000313|EMBL:ABI62873.1, ECO:0000313|Proteomes:UP000001963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1260 / CGDNIH1 {ECO:0000313|Proteomes:UP000001963};
RX PubMed=17827295; DOI=10.1128/JB.00793-07;
RA Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E.,
RA Kupko J.J.III., Barbian K.D., Babar A., Dorward D.W., Holland S.M.;
RT "Genome sequence analysis of the emerging human pathogenic acetic acid
RT bacterium Granulibacter bethesdensis.";
RL J. Bacteriol. 189:8727-8736(2007).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000394; ABI62873.1; -; Genomic_DNA.
DR AlphaFoldDB; Q0BQM9; -.
DR STRING; 391165.GbCGDNIH1_1975; -.
DR KEGG; gbe:GbCGDNIH1_1975; -.
DR eggNOG; COG4258; Bacteria.
DR HOGENOM; CLU_009099_0_0_5; -.
DR Proteomes; UP000001963; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR017841; Hopanoid_biosynth_HpnN.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR NCBIfam; TIGR03480; HpnN; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001963};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 283..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 724..744
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 777..797
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 809..833
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 845..865
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 321..438
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 874 AA; 92830 MW; AB1516394E624799 CRC64;
MREPAGMGLK IMGSTALLTE ATRFCRRRAL WVVLAAMVLA GLSLTHAAHH LGVSTNTDEL
FASSLPWRQR QVAYEKNFPQ NQDLLVAVVD GSIPEEAEAT ADALTKALSE DKEHFLSVQQ
PGALPYFQKE GLLFLDQKSL SSLLDQTIDA QPFLGQLTAD PSARGLFAAL SLVAMGVSRG
EANLQPFMPA LQGFDDALRQ AADGHPKPLS WENLLAGPLA QQAGQYRFVL AQPRLDYDAL
EPGGAATAVL RHIAAGLEFV RTGHAHVRIT GPVALADEEF STVAHGMVEG TLISIALITL
WLFLALRSWR LILPVLATLM LGLTLTIGFA SVAVGTLNLV SVAFAILFVG IAVDFAIQYC
VRFREVRHEI ADPAISLPET TRRVGGQILV AAAATAAGFL AFVPTSFEGV AELGLIAGVG
MVIAFLCTMT FLPAMLSLFR PRAEGREIGF AVGMPLDRTL LRWRRPVLLV FALIAVSGIA
LLSRLTFDSD PLHTKNPNTE AMRTLYGMMG DPMTNPYSAD ILVANREQAE ALAKKLEKLP
TVAEVLTLSS FVPDNQDEKL ALVADAASLL GPTLTPHTPP SSVTPEQIRL AISAALGQIR
PALAKLPANH PLAGIAAALD RLSHASDETL LAANAALVRF LPMQLERLRT ALSAEKVSVK
DIPPALAKDW QLPDGRVRVQ AMTSPKASDS AGLHRFAAEV LAVAPDASGS AIVIVETAQT
IVTAFRHAAM GAIAAIMVIL ALALRRVLDA ALVMSALLLS ALMTVVVISL LPMALNFANI
IALPLLLGVG VSFNIYFVMN WRAGVSGFLA TATARAVIFS ALTTATAFGS LALSEHPGTA
SMGNLLMISL GCTLVASLIY IPALLSGLRR RGQA
//
