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Database: UniProt
Entry: Q0BRN5_GRABC
LinkDB: Q0BRN5_GRABC
Original site: Q0BRN5_GRABC 
ID   Q0BRN5_GRABC            Unreviewed;       615 AA.
AC   Q0BRN5;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   12-AUG-2020, entry version 83.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   OrderedLocusNames=GbCGDNIH1_1619 {ECO:0000313|EMBL:ABI62517.1};
OS   Granulibacter bethesdensis (strain ATCC BAA-1260 / CGDNIH1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Granulibacter.
OX   NCBI_TaxID=391165 {ECO:0000313|EMBL:ABI62517.1, ECO:0000313|Proteomes:UP000001963};
RN   [1] {ECO:0000313|EMBL:ABI62517.1, ECO:0000313|Proteomes:UP000001963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1260 / CGDNIH1 {ECO:0000313|Proteomes:UP000001963};
RX   PubMed=17827295; DOI=10.1128/JB.00793-07;
RA   Greenberg D.E., Porcella S.F., Zelazny A.M., Virtaneva K., Sturdevant D.E.,
RA   Kupko J.J.III., Barbian K.D., Babar A., Dorward D.W., Holland S.M.;
RT   "Genome sequence analysis of the emerging human pathogenic acetic acid
RT   bacterium Granulibacter bethesdensis.";
RL   J. Bacteriol. 189:8727-8736(2007).
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake system.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362098}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|RuleBase:RU362098}.
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DR   EMBL; CP000394; ABI62517.1; -; Genomic_DNA.
DR   RefSeq; WP_011632321.1; NC_008343.2.
DR   STRING; 391165.GbCGDNIH1_1619; -.
DR   EnsemblBacteria; ABI62517; ABI62517; GbCGDNIH1_1619.
DR   GeneID; 31476291; -.
DR   KEGG; gbe:GbCGDNIH1_1619; -.
DR   eggNOG; COG0370; Bacteria.
DR   HOGENOM; CLU_013350_3_2_5; -.
DR   KO; K04759; -.
DR   OMA; PLGYDWK; -.
DR   BioCyc; GBET391165:G1G6T-1653-MONOMER; -.
DR   Proteomes; UP000001963; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR006073; GTP_binding_domain.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   PRINTS; PR00326; GTP1OBG.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022496,
KW   ECO:0000256|RuleBase:RU362098}; Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|ARBA:ARBA00022496,
KW   ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001963};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM        222..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        278..300
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        397..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        449..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        545..567
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   TRANSMEM        587..607
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362098"
FT   DOMAIN          7..175
FT                   /note="FeoB-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51711"
SQ   SEQUENCE   615 AA;  67153 MW;  3D21B6B0BE6C932C CRC64;
     MSTTTHPLRI ALVGNPNCGK TALFNRLTGS RQKVANYAGV TIERKSGRVT TPSGRSVQVL
     DLPGTYSLHA ASPDEAVTRD VCLGRYRGED PPDLLLCVIA ATNLRLHLRF LLEVRQLGRP
     VVAVINMMDA VEKQGLHIDI PHLSEALGIP VVTAIGTQRN GADNLLRLLD TLPPDLPPPP
     PTNTNADLHA EVRAMLDRCI TRIAPERPTL EERLDRWVLH PVWGMLLLTL LMFAMFQAVF
     SWAKPIMDFL QDTMDHLGDV AGTALPEGPL RGLISDGVIA GAGTVIVFLP QILVLFLWIL
     TLEASGYLPR AAFLLDRFMA TAGLSGRSFI PLLSSFACAV PGIMAARTIQ NPRDRMLTIL
     IAPLMTCSAR LPVYALLIGA FIPAHTILGL FNLQGLVLFA LYLAGILSAL LVARVLKRGT
     VEEQPLLLEL PPYRLPSLRS LAIELWQRAY IFLRRVGTII VSVSILLWAL SSFPSPPPGA
     TGPAINYSLA GQIGQAMLLV FEPIGFTWQI CIALIPGLAA REVAVSALAT VYSITADKDH
     AAEKLMPLLS SQWSMATAFS LMAWYVYAPQ CFSTLAVIRR ETGGWKMVWI SAGYLFGLAY
     LLSFLTYRIT RLFTG
//
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