ID Q0C010_HYPNA Unreviewed; 574 AA.
AC Q0C010;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Carbohydrate kinase, FGGY family {ECO:0000313|EMBL:ABI76495.1};
DE EC=2.7.1.- {ECO:0000313|EMBL:ABI76495.1};
GN OrderedLocusNames=HNE_2237 {ECO:0000313|EMBL:ABI76495.1};
OS Hyphomonas neptunium (strain ATCC 15444).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomonadales;
OC Hyphomonadaceae; Hyphomonas.
OX NCBI_TaxID=228405 {ECO:0000313|EMBL:ABI76495.1, ECO:0000313|Proteomes:UP000001959};
RN [1] {ECO:0000313|EMBL:ABI76495.1, ECO:0000313|Proteomes:UP000001959}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15444 {ECO:0000313|EMBL:ABI76495.1,
RC ECO:0000313|Proteomes:UP000001959};
RX PubMed=16980487; DOI=10.1128/JB.00111-06;
RA Badger J.H., Hoover T.R., Brun Y.V., Weiner R.M., Laub M.T., Alexandre G.,
RA Mrazek J., Ren Q., Paulsen I.T., Nelson K.E., Khouri H.M., Radune D.,
RA Sosa J., Dodson R.J., Sullivan S.A., Rosovitz M.J., Madupu R.,
RA Brinkac L.M., Durkin A.S., Daugherty S.C., Kothari S.P., Giglio M.G.,
RA Zhou L., Haft D.H., Selengut J.D., Davidsen T.M., Yang Q., Zafar N.,
RA Ward N.L.;
RT "Comparative genomic evidence for a close relationship between the
RT dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter
RT crescentus.";
RL J. Bacteriol. 188:6841-6850(2006).
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DR EMBL; CP000158; ABI76495.1; -; Genomic_DNA.
DR RefSeq; WP_011647231.1; NC_008358.1.
DR AlphaFoldDB; Q0C010; -.
DR STRING; 228405.HNE_2237; -.
DR KEGG; hne:HNE_2237; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG0631; Bacteria.
DR HOGENOM; CLU_034273_0_0_5; -.
DR Proteomes; UP000001959; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR036457; PPM-type-like_dom_sf.
DR InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24351; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR PANTHER; PTHR24351:SF243; RIBOSOMAL PROTEIN S6 KINASE; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13672; PP2C_2; 1.
DR SMART; SM00331; PP2C_SIG; 1.
DR SMART; SM00332; PP2Cc; 1.
DR SUPFAM; SSF81606; PP2C-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51746; PPM_2; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABI76495.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000001959};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ABI76495.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 555..572
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..240
FT /note="PPM-type phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51746"
FT DOMAIN 273..529
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
SQ SEQUENCE 574 AA; 61996 MW; 673FCDC1B41BD94D CRC64;
MRPAPLRLSV GQWSDRGQKE TNQDFHGALI PQGAVLALKG ASFAVADGVS SSRFGGEAAE
IAVKSFLTDY YCTSDAWSVK TSARRVLEAT NSWLFGQTRA RTRGEGADGG YVTTFSALVI
KGRVAHLLHV GDGVIGRLRQ GAFEPLTEPH RVVLSPAETY LGRALGAGAD VEIDYRSVAL
SEGDLFVLAT DGAADHIPWR ELSAHLNAQA GDLDLAAARL VAAAKANGSD DNLTVQIIRI
DALPESDASD MIRAAQDFPP PPPLDALSEI DGLRILRKLH ANARSHVYLV LDPATHRRLV
LKAPAAELCA DPVLLRRFMM EEWVARRVSS PHIVPAADLG RARSYLYVLL EFVDGQSLRQ
LMNDQPELPL ETVRTLLEQI VAGVRALHRK EIAHGDLRPE NILIDGTGGV QLIDFGSAHV
AGIADSAIAL PPAALGALQY AAPELLLGEP PGRASDQFAI GVIAYELLTG RLPYGAAGGK
VRSDKNRRAL TYQPATRAGQ PLPAWINGAL RTATDPLARR RYEALSEFLA DLRAPNPRFL
RERHAPLIER NPLRFWQGLC ALLAALSLFL AIRG
//
