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Database: UniProt
Entry: Q0C9E6
LinkDB: Q0C9E6
Original site: Q0C9E6 
ID   SET9_ASPTN              Reviewed;         629 AA.
AC   Q0C9E6;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   16-JAN-2019, entry version 59.
DE   RecName: Full=Histone-lysine N-methyltransferase set9;
DE            EC=2.1.1.43;
DE   AltName: Full=SET domain protein 9;
GN   Name=set9; ORFNames=ATEG_09688;
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=341663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156;
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M.,
RA   Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S.,
RA   White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C.,
RA   Denning D.W., Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Histone methyltransferase that specifically methylates
CC       'Lys-20' of histone H4. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-lysyl-[histone] + S-adenosyl-L-methionine = H(+) +
CC         N(6)-methyl-L-lysyl-[histone] + S-adenosyl-L-homocysteine;
CC         Xref=Rhea:RHEA:10024, Rhea:RHEA-COMP:9845, Rhea:RHEA-COMP:9846,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:29969, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:61929; EC=2.1.1.43;
CC         Evidence={ECO:0000255|PROSITE-ProRule:PRU00900};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. Chromosome
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. Suvar4-20 subfamily. {ECO:0000255|PROSITE-
CC       ProRule:PRU00900}.
DR   EMBL; CH476608; EAU29879.1; -; Genomic_DNA.
DR   RefSeq; XP_001218310.1; XM_001218309.1.
DR   ProteinModelPortal; Q0C9E6; -.
DR   SMR; Q0C9E6; -.
DR   STRING; 33178.CADATEAP00004009; -.
DR   EnsemblFungi; EAU29879; EAU29879; ATEG_09688.
DR   GeneID; 4354340; -.
DR   EuPathDB; FungiDB:ATEG_09688; -.
DR   HOGENOM; HOG000214006; -.
DR   OMA; IYLPDCP; -.
DR   OrthoDB; 953612at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:InterPro.
DR   InterPro; IPR025783; Hist-Lys_N-MeTrfase_SET9.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS51567; SAM_MT43_SUVAR420_1; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Chromatin regulator; Chromosome; Complete proteome; Methyltransferase;
KW   Nucleus; Reference proteome; S-adenosyl-L-methionine; Transferase.
FT   CHAIN         1    629       Histone-lysine N-methyltransferase set9.
FT                                /FTId=PRO_0000281800.
FT   DOMAIN      120    234       SET. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00190}.
SQ   SEQUENCE   629 AA;  71319 MW;  2D085F90ED32A649 CRC64;
     MAPSKARSSP AVERRDRLTL AKLASYDDVA TDALVDRAYF WTNTRKNRTK YIPVRGIMDD
     KVAEILLHHV IVAKDTVKAE RELLAISGIK KYMAKLPSDR EKEWFRRHLR KYIQMYLPDC
     PFEVTTTNRY TITEHEAAIC ARKFIKQGQE IKYLSGTLVP MTREEEQDLD LKRKDFSIVM
     SSRRKTPSFF LGPARFANHD CDANGRLVTR GSEGMQVVAT RDIEIGEEIT VSYGEDYFGI
     DNCECLCLTC ERAVRNGWAP QVDSEASSTA STPALNDETK SAHGSTSPQK RKYAPDADSD
     ASASPTPQKR RKFSRQYSKL RTEVSLSGDV TAIEPDPEQN TKIAVETTTD VPKDKPATNG
     VTENESNARV SENQRATSDR EPSSPLGVDE SQNSSASTAP TSLFDVGIKL EESTEAFTQE
     TLTTTKAGSV ADSHGDGDCR QLTAGIEQEA LSELSESLEL DDKSGTVVKR RKRRTRRQVV
     PSVEDESHRV RVPGDYTKTS KLLAQSYDRW VECRTCKTWF LQHNSYLTRR ECPRCERHSM
     LYGFQWPKTD KDGPLDDEER VMDHRTVHRF LYPEEEARIS RRDRGVSFGV TPTPELSEPR
     TETEDSEACD ERRNTRASRR RTQSLRMTM
//
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