ID Q0CDV5_ASPTN Unreviewed; 236 AA.
AC Q0CDV5;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 03-MAY-2023, entry version 59.
DE RecName: Full=Alpha-acetolactate decarboxylase {ECO:0000256|ARBA:ARBA00020164};
DE EC=4.1.1.5 {ECO:0000256|ARBA:ARBA00013204};
GN ORFNames=ATEG_08129 {ECO:0000313|EMBL:EAU31302.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU31302.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2S)-2-acetolactate + H(+) = (R)-acetoin + CO2;
CC Xref=Rhea:RHEA:21580, ChEBI:CHEBI:15378, ChEBI:CHEBI:15686,
CC ChEBI:CHEBI:16526, ChEBI:CHEBI:58476; EC=4.1.1.5;
CC Evidence={ECO:0000256|ARBA:ARBA00001784};
CC -!- PATHWAY: Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-
CC butane-2,3-diol from pyruvate: step 2/3.
CC {ECO:0000256|ARBA:ARBA00005170}.
CC -!- SIMILARITY: Belongs to the alpha-acetolactate decarboxylase family.
CC {ECO:0000256|ARBA:ARBA00007106}.
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DR EMBL; CH476605; EAU31302.1; -; Genomic_DNA.
DR RefSeq; XP_001216750.1; XM_001216750.1.
DR AlphaFoldDB; Q0CDV5; -.
DR STRING; 341663.Q0CDV5; -.
DR EnsemblFungi; EAU31302; EAU31302; ATEG_08129.
DR GeneID; 4353475; -.
DR VEuPathDB; FungiDB:ATEG_08129; -.
DR eggNOG; ENOG502S81V; Eukaryota.
DR HOGENOM; CLU_072561_0_0_1; -.
DR OMA; GEAYHFT; -.
DR OrthoDB; 2583430at2759; -.
DR UniPathway; UPA00626; UER00678.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0047605; F:acetolactate decarboxylase activity; IEA:UniProtKB-EC.
DR GO; GO:0045151; P:acetoin biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd17299; acetolactate_decarboxylase; 1.
DR InterPro; IPR005128; Acetolactate_a_deCO2ase.
DR PANTHER; PTHR35524; ALPHA-ACETOLACTATE DECARBOXYLASE; 1.
DR PANTHER; PTHR35524:SF1; ALPHA-ACETOLACTATE DECARBOXYLASE; 1.
DR Pfam; PF03306; AAL_decarboxy; 1.
DR PIRSF; PIRSF001332; Acetolac_decarb; 1.
DR SUPFAM; SSF117856; AF0104/ALDC/Ptd012-like; 1.
PE 3: Inferred from homology;
KW Acetoin biosynthesis {ECO:0000256|ARBA:ARBA00023061};
KW Decarboxylase {ECO:0000256|ARBA:ARBA00022793};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963}.
SQ SEQUENCE 236 AA; 25579 MW; 941060338F71DB3D CRC64;
MANNLYQYSI VSALMHGICS TGPSIRDILA HGDHGLGTVP HLNGEIIIID GEAYHFPPDS
PELRKLAPTD PIPFIMITRF EPTVTKHLPT LTMTALADAC APLLPAQQNR FVSVRLEAVF
PRISFRVIPA QTRPKEPLAA LAKRQTVREE THVRGVLFGF WSPAFASGFS VAGFHLHFLS
ADRSAGGHVM GFEAEDVRLA AAGIGEYHVQ LPDDREFNEE TIGLVGAGDI HAAEGA
//
