ID Q0CF76_ASPTN Unreviewed; 703 AA.
AC Q0CF76;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE RecName: Full=Golgi apyrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ATEG_07658 {ECO:0000313|EMBL:EAU31920.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU31920.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283, ECO:0000256|RuleBase:RU003833}.
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DR EMBL; CH476604; EAU31920.1; -; Genomic_DNA.
DR RefSeq; XP_001216279.1; XM_001216279.1.
DR AlphaFoldDB; Q0CF76; -.
DR STRING; 341663.Q0CF76; -.
DR EnsemblFungi; EAU31920; EAU31920; ATEG_07658.
DR GeneID; 4323011; -.
DR VEuPathDB; FungiDB:ATEG_07658; -.
DR eggNOG; KOG1386; Eukaryota.
DR HOGENOM; CLU_010246_3_0_1; -.
DR OMA; WHDALFD; -.
DR OrthoDB; 180318at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0017110; F:nucleoside diphosphate phosphatase activity; IEA:UniProt.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
DR PROSITE; PS01238; GDA1_CD39_NTPASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Hydrolase {ECO:0000256|RuleBase:RU003833};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 511..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 590..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 662..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 597..624
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..698
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 137
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 174..178
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 703 AA; 77482 MW; 715262A373674FD0 CRC64;
MESSWTPGTR VHVYRWLNHD AARKTANAQK LKSLPEIKTK PSWTKKIHPG VSSFADRPED
VGPQHLEELL QHAQEIIPRD AIKDTPIFLL ATAGMRLLPD VQRNLLLEQI CSYASANSDF
LLPDCGVHIQ VIPGVTEGLY GWIATNYLLG SFDEPEAHDH GKGHHTYGFL DMGGASAQIA
FAPNATESEK HANDLTLLRL RNLDGSEQEH RVFVTSWLEF GVHEARRRYI EALQEANMID
TSQELPDPCL PAGLRTTIDG KPLPVDGEEG VALVGTGKFD ECLRQTYPLL DKDAPCADEP
CLLHGIHVPA IDFDVNHFVG ISEYWHSTHD IFELGGHKVS YNFKTYQERV QAFCSQDWED
IEEGIHLHKW GKKLDQELAS EICFKASWII NVLHDGIGVP RVSLEEAGSA HNGTKELLSQ
GRIKGYIDPF QAVHKIDSTE VSWTLGKMVL YASSQVPVEV DEALPVGFGS NVDGVPADFQ
FPSVELLPPT EGLHQESWHD ALFEGGSSRR VPGFILFLSI IIMALFFLCG RNRRMRMYHK
INQLFHRGGP SHPNHPKKRR FLGGKLPFFG SRSPSYERVL EDGVGEFDMG GLDSGRSSSE
GGRSSDADSA SFLPPNRTSS WGSGNAPSLK YGLDNSSTGT IGLGITAGSG VNAMDRTGLV
VRTESRDHLA PIALGPTTNG RRSRAGSPTR SHRSPALTPL SHD
//
