ID Q0CI53_ASPTN Unreviewed; 1994 AA.
AC Q0CI53;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 24-JAN-2024, entry version 86.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=ATEG_06631 {ECO:0000313|EMBL:EAU33175.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU33175.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CH476602; EAU33175.1; -; Genomic_DNA.
DR RefSeq; XP_001215809.1; XM_001215809.1.
DR STRING; 341663.Q0CI53; -.
DR EnsemblFungi; EAU33175; EAU33175; ATEG_06631.
DR GeneID; 4322321; -.
DR VEuPathDB; FungiDB:ATEG_06631; -.
DR eggNOG; KOG2068; Eukaryota.
DR HOGENOM; CLU_001793_0_0_1; -.
DR OMA; CLITPRG; -.
DR OrthoDB; 1748at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd16618; mRING-HC-C4C4_CNOT4; 1.
DR CDD; cd12438; RRM_CNOT4; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR034261; CNOT4_RRM.
DR InterPro; IPR021858; Fun_TF.
DR InterPro; IPR039780; Mot2.
DR InterPro; IPR039515; NOT4_mRING-HC-C4C4.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR003954; RRM_dom_euk.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR12603; CCR4-NOT TRANSCRIPTION COMPLEX RELATED; 1.
DR PANTHER; PTHR12603:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4; 1.
DR Pfam; PF11951; Fungal_trans_2; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF14570; zf-RING_4; 1.
DR SMART; SM00361; RRM_1; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT TRANSMEM 801..822
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 829..849
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..62
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 231..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 434..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 737..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 908..1239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 319..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 434..467
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 908..926
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..985
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1018..1038
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1089
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1099..1126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1127..1149
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1172..1186
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1192..1239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1994 AA; 215436 MW; F9279C037665D9B1 CRC64;
MSSRQQIDSV IDDDDEFCPL CIEEFDLSDK NFKPCPCGYQ ICQFCYNNIK THSEEGRCPN
CRRVYDESTI QYKVPDADEF KADLALKHRK AAAAKKKEAE KREIEASSRK NLAGVRVVQK
NLVYVIGLNP TIRDESQLLQ TLRGKDYFGQ YGDIEKIVVS KAKPGGNPHQ GIGVYVTYAR
KADAATCIAA VDGSVNGDRV LRAQYGTTKY CSSFLRNEQC HNRNCTFLHE TGEESESYSR
QDLSSINTLS SQRSNPTAPG GPGPSIPPHV ARSSAVPLSQ PMRRQPSKDD PAVIRPPDGS
ALPSSASWAN KDAVMHRTRR TSLSGSQASN SPRPAPATVA TGSDESKRTE KPSAGTQDRR
QTPLPEPRPG TPRTTEAQPA ADPVSPLLDG LIKAVNSPDF KFVFSAAGLP AEEVTRIENH
PSFIDPYGGV KRRAMREKAE QERVKREQEL LQSAAEEEER RESGSLQLGG EPDDANPPRG
RTGRDSHGAI QPPSQQGTTT NSAVGSPVSA ASHHFQGLNL ASRSLTPLQQ QQLMLLKSAG
TQQPGLVDPL QSVALDQAAQ VRQGLLQSQM AQFSALQAQN RPNSRFSFAS EAAAKNLPNV
RMLSQMQSGT PNPLAAPSPQ HGLASNFYTS GVQGPPPGLK TAGTPPISGG GMFAQGHGFT
TNANLGLGGN LGKQDANPEL MRELLRGRGA TNAGGLQGPD AAKREFMFPF LQQHQTPPPL
TPANGLLSSF YGPQAGNLSD AGPQKQKKKG KKQRHANTSS GGGGVVDLAD PSILQARMHQ
VGANAAAGQA LYGSQGQASN LLFLMFCFFV PIFRMAWGLV AFAWTPCVFA VHGASVALHL
GATSVWSWLY SSARAGTPTL PPGLPLPHAH PASSLLHSPI NPSSPTLSVS GPPPGLNIPF
HRFGTPSQSF QELTSRQQSP GSKDTPEDAS PSARVKNVSE ISLGSPVPKS AHKARSQSKD
ELTVSADKTP KKGDSPEEKV SLAKGKPIKL DLNTSQASEV TKPEGMGQPH HHPAPSSAVG
SRPNTPMTAA SRLSDSSAPR QPRVLRVVDT PKAETPPPAS ATQSVSSLPA VNKARSRRPS
ISSLSRPDTP GDLGSEADLY TSASVSRANS PPASSRIGSA PVRSVTKSQA KKERRQKAKE
AEAKKQEATS VAEEPVQAPI IGRKRKTKKA PTPSAEQPST PETTIEPAKP SEKASDTSDK
AEPKVEPKKT KAKDKAVKDP KPEPVEVKEE PKKPQEAWRT KNTVEQMIKD SEAFGTSIKE
LFAERTSSLQ VLLAQLHKSG QLDLNSHPLF NPPNLSQRVD MKCTSDDYET LKQPIELTDE
HRRALLRGEP VRINPDSPLL KDRCLISPRG CVLHHLTPEE EERYLALEKH VAWAMDSFQE
YPAVPITEPD MSNRGGGLDA LFATPENFNV CWVDEAAGSL ACTTSSTGLT DSPTVSVTGA
PPNVLSAMEA DSTRSHNWAI ANTAELVNAT ATSVRSFAAA TAKHMLGAAG VVVGNMPDLD
DVVGMTDDEL RSFAVKSQKE LEVSRKELDS IDKKLSALVK RNKKLAQQAL TTSVESSTAP
VKGPSKANEK LSVSRALPVP STERSICIFL HHYVLSDALL GAAAHLTVSQ VVGHMKSSQA
VHYAVSAVGL AMLANMGDAP GVADEARAHY AQALRLTNVA LSNKAKALEN TTLNAVIILG
MFEVMLGGTP KSLENSQRHL AGAAALLEVW GSRQACSLTG IQLFTQLRTD LTVNLLLEMA
NCLRTQTHVP DTVRRLSGFV QSCRSKEDVQ VEVLVELIAE MADLLADVKG NGIPNPLEAM
GRAWVIDSRL EAWSLGLPQR WQYTIHHIPA NLPGVISELA FDGQYHVYQD IWACNIWNYY
RNARVLLNLL IRDRLVVYLT IQPYPEWKPL LDQTRSNIQR FSVDILLSVS FAIAVQFASL
QRGRDHTRPG GYLGAYYVIW PLYVAVSVQI PGTPLWEWAV GRLEYIGRIM GIGQALLMAR
ALRRELERTE TFDT
//
