ID Q0CIT1_ASPTN Unreviewed; 342 AA.
AC Q0CIT1;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Farnesyl pyrophosphate synthetase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ATEG_06403 {ECO:0000313|EMBL:EAU32947.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU32947.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CH476602; EAU32947.1; -; Genomic_DNA.
DR RefSeq; XP_001215581.1; XM_001215581.1.
DR AlphaFoldDB; Q0CIT1; -.
DR STRING; 341663.Q0CIT1; -.
DR EnsemblFungi; EAU32947; EAU32947; ATEG_06403.
DR GeneID; 4321953; -.
DR VEuPathDB; FungiDB:ATEG_06403; -.
DR eggNOG; KOG0711; Eukaryota.
DR HOGENOM; CLU_028376_1_0_1; -.
DR OMA; NEASHRT; -.
DR OrthoDB; 509027at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0046165; P:alcohol biosynthetic process; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR039702; FPS1-like.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR11525:SF0; FARNESYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR11525; FARNESYL-PYROPHOSPHATE SYNTHETASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 342 AA; 39114 MW; 46E4F818E9216F4A CRC64;
MANHENFKSV LEVLANEIQE DLSERKAPSA IRDRLQQCLL ANTKDGKLNR GLTVVDTGCT
LLQRPPTPAE FQDLSILGWM VEMFQASYLV SDDIMDNSEY RRGKLCWYRR DEVGLTAIND
AAFLKSLMFS LLKKHFQHHA EYVGILELLN EASHRTELGQ LSDADMAVKA RGLDQMTVEA
YSFIARNKTA FYSFYLPIAL ALHYLRLANE SNLKQVKTIM LPMGEYFQVQ DDYLDCFGDP
SVTGKVGTDI EDHKCTWLIV RALTLCSAEQ RQVLDFSYGR QGPVHDTAVR TIFHDLGLEK
LYREYEEEMV HESQKAIDRL SEQNGLKDVF QGALEKIARR DK
//
