ID Q0CJE0_ASPTN Unreviewed; 548 AA.
AC Q0CJE0;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=ATEG_06194 {ECO:0000313|EMBL:EAU33955.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU33955.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CH476601; EAU33955.1; -; Genomic_DNA.
DR RefSeq; XP_001215372.1; XM_001215372.1.
DR AlphaFoldDB; Q0CJE0; -.
DR STRING; 341663.Q0CJE0; -.
DR EnsemblFungi; EAU33955; EAU33955; ATEG_06194.
DR GeneID; 4321620; -.
DR VEuPathDB; FungiDB:ATEG_06194; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_13_7_1; -.
DR OMA; SQVNWTV; -.
DR OrthoDB; 2787978at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23502; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23502:SF139; TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G13160)-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 66..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..213
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..497
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..525
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..529
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 260..288
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 60313 MW; C151EAD44B6ADC04 CRC64;
MSTTVLSMKD EAESTKNTAM KAQMDATDIV DREKAHTAEQ NGLKIHPQPT SDPLDPLNWS
RLQKHTILGI VMLKYFLFTY ITTTTVPSFP EIQTQFDISY SQVNWTVAIP ALGLSIGPLF
WSSLSDIYGR RIIFILGTVI ALVSTVGAAV ADTYGGYMTA RFFQGFGVSP GSTVGMAVVN
DLFFDYERGQ KLGLWVLAID SGLLLGPTFG GFLNLVSAAW INWFNAILFA ALLVLELALM
PETLYPRSLM LQLMSRDPLT APSSDIESPA EKPVPATTTP PGKMNDSTTQ MVEVSRTKNL
PFINLRPVPG MRHPKPWDAV VRFFLTFQFP VVVIAVIGYS FVWYWWVLSV ITMVPAAYAS
YTPLIQGLLF LGLLIGTVVS EVCCSGRLSD YIVGKLARRN GSVRVAEMRL WLAYPAILLT
AVGLILWGVS VDKSYHWMVG QVAFFLSPVA AGIQIGNTVT SSYIIDSYPL QSTSVVIFYA
VFLNLSAFIN PFFIANWQAA VGWTWTFTAQ ALIVVVAGTA VFLILQRFGA LLRAKAPVPS
WVNPEFDS
//
