ID   Q0CKE9_ASPTN            Unreviewed;       823 AA.
AC   Q0CKE9;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   24-JAN-2024, entry version 79.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=ATEG_05835 {ECO:0000313|EMBL:EAU33596.1};
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU33596.1, ECO:0000313|Proteomes:UP000007963};
RN   [1] {ECO:0000313|Proteomes:UP000007963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; CH476601; EAU33596.1; -; Genomic_DNA.
DR   RefSeq; XP_001215013.1; XM_001215013.1.
DR   AlphaFoldDB; Q0CKE9; -.
DR   STRING; 341663.Q0CKE9; -.
DR   EnsemblFungi; EAU33596; EAU33596; ATEG_05835.
DR   GeneID; 4321749; -.
DR   VEuPathDB; FungiDB:ATEG_05835; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   HOGENOM; CLU_004747_7_1_1; -.
DR   OMA; MFKDMTI; -.
DR   OrthoDB; 5474206at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          442..689
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   823 AA;  94866 MW;  00E74E749D014843 CRC64;
     MAMRARQKIR APRRGPTANK TDDFDSNWNI LSSALRQIHT KNASNLSFEQ LYRNAYNIVL
     MTRGNDLYGH VQGWEQQWLE DEVRKRVTAA ISPVLLLGKD PADVQDQANE RRAAGEKFLE
     IMRELWEDHQ LCMGMITDVL MYMDRVVTSD HKKPSTYVAA MALFRDYVLH SPIRDDSDTT
     VGDVLKSTIL FMIHLERFGH VIDRALIRHC VYMLEGLYET IQEEESKKLY LTMFEPAFLE
     TSKRFYHDEG KRLLETADAT VFCKRAQERI AEERERCTYT LSPLTEPKIK EVLDNELIRA
     HISEVINLEG TGVRTMIDND RLDALHSIYV LSARVDSKKP PLTAAVQKRI VEIGREINAS
     AIQQGQAPVA KPAEKTADGA KKAVEKEKPV NQQTASAIKW VDDVLALKTK FDKIWEKSFQ
     SDQVMQSSIT TSFSEFINTN TRSSEHLSLF FDENLKKGIK GKTDDEVDAL LENGITLLRY
     IKDKDLFEAY YKKHLSRRLL MKRSVSMDAE RQMISKMKME VGNQFTQRLE SMFKDMTISE
     DLTTSYKKHI QQSGDPDQKR VDLDINVLTS TMWPMEIMSN TRDDQVQLSC IFPKEIDSVR
     QSFEKFYLDK HSGRKLSWQA SMGTADIRAT FHRSNGKVQR HELNVSTYAM VILMLFNDVE
     SGESLTFEEI LERTRIPDHD LKRNLQSLAV APKTRVLKKD PMSKDVNPGD KFFFNNEFQS
     PFMKVRIGVV SGGASKVENQ DQRKETEKRM NDERGASIEA AVVRIMKQRK KLVHSQLMTE
     VLSQLSSRFS PDVNMIKKRI ESLIDREYLE RVHDDPPTYG YLA
//