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Database: UniProt
Entry: Q0CN52_ASPTN
LinkDB: Q0CN52_ASPTN
Original site: Q0CN52_ASPTN 
ID   Q0CN52_ASPTN            Unreviewed;       370 AA.
AC   Q0CN52;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   08-MAY-2019, entry version 64.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=ATEG_04882 {ECO:0000313|EMBL:EAU35329.1};
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU35329.1, ECO:0000313|Proteomes:UP000007963};
RN   [1] {ECO:0000313|Proteomes:UP000007963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K.,
RA   LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M.,
RA   Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S.,
RA   White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C.,
RA   Denning D.W., Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
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DR   EMBL; CH476599; EAU35329.1; -; Genomic_DNA.
DR   RefSeq; XP_001214060.1; XM_001214060.1.
DR   STRING; 33178.CADATEAP00006112; -.
DR   EnsemblFungi; EAU35329; EAU35329; ATEG_04882.
DR   GeneID; 4320140; -.
DR   EuPathDB; FungiDB:ATEG_04882; -.
DR   HOGENOM; HOG000220501; -.
DR   OMA; VMENVAN; -.
DR   OrthoDB; 1034517at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000007963};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007963};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361}.
FT   DOMAIN       55    353       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   370 AA;  40431 MW;  25B89B2737A29D2F CRC64;
     MSFFIENRHV GDKSHLEDSR IRGYNPLTPP NLLQHEIALT EKSRQTVMEG RDEAIAVVHG
     TDKHRLLVVI GPCSIHDPEM ALEYCDRLLK MKEKYKDELL IVMRSYLEKP RTTVGWKGLI
     NDPDIDNSFQ INKGLRTSRQ LFVDLTNKGM PIASEMLDTI SPQFLADCLS VGAVGARTTE
     SQVHRELASG LSFPVGFKNG TDGSLDVAVD AIGSVKHPHH FLSVTKPGVV AIVGTVGNPD
     CFVILRGGKK GPNYDAQSIA EAKAKLTSQG MTPRLMVDCS HGNSQKNHKN QPKVAAVLAE
     QIAAGETAIM GVMIESNINE GNQKVPPEGK AGLKYGVSIT DACINWEDTE LVLENLAQAV
     RTRKEKFGAN
//
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