ID   Q0CV67_ASPTN            Unreviewed;       635 AA.
AC   Q0CV67;
DT   17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   17-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   RecName: Full=FAD monooxygenase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=ATEG_02417 {ECO:0000313|EMBL:EAU37379.1};
OS   Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU37379.1, ECO:0000313|Proteomes:UP000007963};
RN   [1] {ECO:0000313|Proteomes:UP000007963}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA   Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA   Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA   Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA   Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA   Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA   Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA   Nierman W.C., Milne T., Madden K.;
RT   "Annotation of the Aspergillus terreus NIH2624 genome.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PheA/TfdB FAD monooxygenase family.
CC       {ECO:0000256|ARBA:ARBA00007801}.
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DR   EMBL; CH476596; EAU37379.1; -; Genomic_DNA.
DR   RefSeq; XP_001211595.1; XM_001211595.1.
DR   AlphaFoldDB; Q0CV67; -.
DR   STRING; 341663.Q0CV67; -.
DR   EnsemblFungi; EAU37379; EAU37379; ATEG_02417.
DR   GeneID; 4316719; -.
DR   VEuPathDB; FungiDB:ATEG_02417; -.
DR   eggNOG; KOG3855; Eukaryota.
DR   HOGENOM; CLU_009665_9_3_1; -.
DR   OMA; IMAYEPA; -.
DR   OrthoDB; 1386239at2759; -.
DR   Proteomes; UP000007963; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02979; PHOX_C; 1.
DR   Gene3D; 3.40.30.20; -; 1.
DR   Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR   InterPro; IPR002938; FAD-bd.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR012941; Phe_hydrox_C_dim_dom.
DR   InterPro; IPR038220; PHOX_C_sf.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR43004:SF7; P-HYDROXYBENZOATE-M-HYDROXYLASE; 1.
DR   PANTHER; PTHR43004; TRK SYSTEM POTASSIUM UPTAKE PROTEIN; 1.
DR   Pfam; PF01494; FAD_binding_3; 1.
DR   Pfam; PF07976; Phe_hydrox_dim; 1.
DR   PRINTS; PR00420; RNGMNOXGNASE.
DR   SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   3: Inferred from homology;
KW   FAD {ECO:0000256|ARBA:ARBA00022827};
KW   Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007963}.
FT   DOMAIN          8..366
FT                   /note="FAD-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01494"
FT   DOMAIN          411..587
FT                   /note="Phenol hydroxylase C-terminal dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07976"
SQ   SEQUENCE   635 AA;  70904 MW;  38A0E30615FC0099 CRC64;
     MAPSDNQYDI VIIGAGPVGI LLSLCMSRWG YKVKHIDNRP VPTATGRADG IQPRSTEILR
     NLGLKRQIMA YHPAKVYDVA FWDPLPGGKG IHRTGSWPSC PRFIDTRYPF TTLVHQGKIE
     RVFIDEIEKA GGTIERPWTI VGFKNDGLDK TYPVEVQLKC IDTNVIETVR TKYLFSGEGA
     RSFVRQQLNI PIHHKDPIAY VWGVMDGVVR TNFPDIETKC TIHSDAGSIM VIPREDNMVR
     LYVQIASSSD PDWNPRKTAT AEEVQATAKK ILAPYWIEWD RVEWYSVYPI GQGISERYTL
     DERVFMGGDA CHTHSPKAGQ GMNTAFHDAL NMAWKLHAVE SGLAERSILS TYESERKDIA
     ETLLNFDAKY AALFSKRRPT AGEVGEASHM VAKVGTDEDE FVKTFKSSCE FTSGYGVAYK
     PNVFNWDESH PAQSPLFGVP GVKLKVGRAF TPTTVTRLAD ANFVDLEQEV PANGAFRIFI
     FAGKQANTKK AISDLAANLE KERSFLSVHR RPDIADVSFF ERHQPHSKLF TICVIYAAEK
     NQVDIDSVPK ILRDYHHHIY ADDIPDVRVP QAQFAAHEKL GFDPEKGGVV VTRPDSHVAC
     TVQLAEGSGT VDALNAYFNA FSTKPIGQDA QQSRL
//