ID Q0CY28_ASPTN Unreviewed; 587 AA.
AC Q0CY28;
DT 17-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 17-OCT-2006, sequence version 1.
DT 24-JAN-2024, entry version 71.
DE SubName: Full=Sorting nexin-41 {ECO:0000313|EMBL:EAU38163.1};
GN ORFNames=ATEG_01406 {ECO:0000313|EMBL:EAU38163.1};
OS Aspergillus terreus (strain NIH 2624 / FGSC A1156).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=341663 {ECO:0000313|EMBL:EAU38163.1, ECO:0000313|Proteomes:UP000007963};
RN [1] {ECO:0000313|Proteomes:UP000007963}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIH 2624 / FGSC A1156 {ECO:0000313|Proteomes:UP000007963};
RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M.,
RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M.,
RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., Denning D.W.,
RA Nierman W.C., Milne T., Madden K.;
RT "Annotation of the Aspergillus terreus NIH2624 genome.";
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004481}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004481}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
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DR EMBL; CH476595; EAU38163.1; -; Genomic_DNA.
DR RefSeq; XP_001208771.1; XM_001208771.1.
DR AlphaFoldDB; Q0CY28; -.
DR STRING; 341663.Q0CY28; -.
DR EnsemblFungi; EAU38163; EAU38163; ATEG_01406.
DR GeneID; 4316116; -.
DR VEuPathDB; FungiDB:ATEG_01406; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_014456_0_0_1; -.
DR OMA; CRRMKEV; -.
DR OrthoDB; 5475877at2759; -.
DR Proteomes; UP000007963; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR CDD; cd06867; PX_SNX41_42; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR044106; PX_Snx41/Atg20.
DR PANTHER; PTHR46979; SORTING NEXIN-41; 1.
DR PANTHER; PTHR46979:SF2; SORTING NEXIN-41; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Autophagy {ECO:0000256|ARBA:ARBA00023006};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007963}.
FT DOMAIN 97..213
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..81
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..243
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..494
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 587 AA; 65091 MW; 1B1608EEBDA2DF2E CRC64;
MWNDEDNNPY GAFDHEAHLS ESLHSATLSP QLYDRENTPP SPSSRSSTQD PPPFLSQQQD
LSDDDNTGEY GAQETSQGYM RKSVYDSRIE QILYENPEMP ILITDAGKNH EGGGSYIVYT
IRTGDLEVRR RYSEFASLRQ TLVNLHPTLI IPPIPEKHTM ADYAAKPTKA KEDTAIIELR
KRMLAVFLNR CRQMKEVRED GVWWRFLDPN VSWSEVLHSH PASSVPKNNL KAPPLDPANP
APAHAWLPVP STSAKLKGAG TSPTEAPGPD VLGRFPPESR KLSEQELDPY FINFEASTRE
LELLLQGNIE KVNRRTLAHL SSLSADLMEL GARYNGFSLS EQSPTVAAAI ERIGQAADTS
YIETEELSSA LGANFAEPMR ESAQFASVVR SVLRYRVLKR VQEEMTRDEL AKKKALLDSL
ERSELEAKRI EQYLNRTSPQ PTGTKPQRSL SASSGTSAPS VSEGDSHQGG SDDGTSIGSD
FPPTHGDSAV PTSPTSPRRP GPGPSSPPAH RKTSSGTFMS NKIFGRISHA VHGFVDVDPE
RTRRDQIGKT KESLLQVAYA RCHLDWARKN LETWTEAKDE VDKIVVR
//
