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Database: UniProt
Entry: Q0E3X4
LinkDB: Q0E3X4
Original site: Q0E3X4 
ID   RH35A_ORYSJ             Reviewed;         627 AA.
AC   Q0E3X4; Q67UX4;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 2.
DT   11-DEC-2019, entry version 86.
DE   RecName: Full=DEAD-box ATP-dependent RNA helicase 35A;
DE            EC=3.6.4.13;
GN   OrderedLocusNames=Os02g0150100, LOC_Os02g05660; ORFNames=OSJNBa0050G13.7;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=18089549; DOI=10.1093/nar/gkm978;
RG   The rice annotation project (RAP);
RT   "The rice annotation project database (RAP-DB): 2008 update.";
RL   Nucleic Acids Res. 36:D1028-D1033(2008).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 168-627.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12869764; DOI=10.1126/science.1081288;
RG   The rice full-length cDNA consortium;
RT   "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT   japonica rice.";
RL   Science 301:376-379(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD box
CC       family of RNA helicases and controls ATP binding and hydrolysis.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX41 subfamily.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAF07814.1; Type=Erroneous initiation; Evidence={ECO:0000305};
DR   EMBL; AP005412; BAD38045.1; -; Genomic_DNA.
DR   EMBL; AP008208; BAF07814.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AP014958; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK060595; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015626564.1; XM_015771078.1.
DR   SMR; Q0E3X4; -.
DR   STRING; 4530.OS02T0150100-02; -.
DR   PaxDb; Q0E3X4; -.
DR   PRIDE; Q0E3X4; -.
DR   KEGG; osa:4328308; -.
DR   eggNOG; KOG0341; Eukaryota.
DR   eggNOG; ENOG410XQQC; LUCA.
DR   HOGENOM; HOG000268792; -.
DR   InParanoid; Q0E3X4; -.
DR   KO; K13116; -.
DR   OrthoDB; 447398at2759; -.
DR   Proteomes; UP000059680; Chromosome 2.
DR   Genevisible; Q0E3X4; OS.
DR   GO; GO:0005681; C:spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   InterPro; IPR001878; Znf_CCHC.
DR   InterPro; IPR036875; Znf_CCHC_sf.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00343; ZnF_C2HC; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF57756; SSF57756; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
DR   PROSITE; PS50158; ZF_CCHC; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Helicase; Hydrolase; Metal-binding; Nucleotide-binding;
KW   Reference proteome; RNA-binding; Zinc; Zinc-finger.
FT   CHAIN           1..627
FT                   /note="DEAD-box ATP-dependent RNA helicase 35A"
FT                   /id="PRO_0000282498"
FT   DOMAIN          213..397
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   DOMAIN          408..568
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00542"
FT   NP_BIND         226..233
FT                   /note="ATP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   ZN_FING         584..601
FT                   /note="CCHC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00047"
FT   MOTIF           182..210
FT                   /note="Q motif"
FT   MOTIF           345..348
FT                   /note="DEAD box"
SQ   SEQUENCE   627 AA;  69242 MW;  7D42E609E57B2909 CRC64;
     MAAATASSPA TAAAANSDDE DNYEEYIPVA KRRAMEADRL RRLRLSKPAP PSSSAAEAAS
     DLPPPPPPPP NQPSAGGGGG GLEASAKPSL LVKATQLKRA APEVTHTEQL IMQEKEMIEH
     LSDRKTLMSV RELAKGITYS DPLKTGWKPP LRLRRMPRAK ADELRRKWHI LVDGDDVPPP
     ARDFRDLRLP EPMLRKLREK GIVQPTPIQV QGLPVVLSGR DMIGIAFTGS GKTLVFVLPL
     IMVALQEEMM MPIVPGEGPF GMIICPSREL AKQTYDVIEQ FLVPLKEAGY PEIRPLLCIG
     GVDMRAQLDV VKKGVHIVVA TPGRLKDLLA KKKMNLDNCR YLTLDEADRL VDLGFEDDIR
     EVFDHFKAQR QTLLFSATMP KKIQNFAKSA LVKPVIVNVG RAGAANLDVI QEVEYVKEDA
     RIIYLLECLQ KTPPPVLVFC ENKADVDYIH EYLLLKGVEA VAIHGGKDQE ERENAIEFFK
     NGKKDVLVAT DVASKGLDFP DIQHVINYDM PAEIENYVHR IGRTGRCGKT GIATTFINKN
     QTETTLLDLK HLLKEAKQRI PPVLAELNDP LEDEETMAKE SGVKGCAYCG GLGHRVTDCP
     KLEHQKSMAI AGSRRDYYGG GGYRGEI
//
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