ID   Q0K251_CUPNH            Unreviewed;       816 AA.
AC   Q0K251;
DT   03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2006, sequence version 1.
DT   27-MAR-2024, entry version 86.
DE   SubName: Full=Two domain protein: VgrG and COG4253 {ECO:0000313|EMBL:CAJ95923.1};
GN   OrderedLocusNames=H16_B1132 {ECO:0000313|EMBL:CAJ95923.1};
OS   Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS   / H16 / Stanier 337) (Ralstonia eutropha).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ95923.1, ECO:0000313|Proteomes:UP000008210};
RN   [1] {ECO:0000313|EMBL:CAJ95923.1, ECO:0000313|Proteomes:UP000008210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC   337 {ECO:0000313|Proteomes:UP000008210};
RX   PubMed=16964242; DOI=10.1038/nbt1244;
RA   Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA   Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA   Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT   "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT   eutropha H16.";
RL   Nat. Biotechnol. 24:1257-1262(2006).
CC   -!- SIMILARITY: Belongs to the VgrG protein family.
CC       {ECO:0000256|ARBA:ARBA00005558}.
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DR   EMBL; AM260480; CAJ95923.1; -; Genomic_DNA.
DR   RefSeq; WP_011617031.1; NZ_CP039288.1.
DR   AlphaFoldDB; Q0K251; -.
DR   STRING; 381666.H16_B1132; -.
DR   GeneID; 57647035; -.
DR   KEGG; reh:H16_B1132; -.
DR   eggNOG; COG3501; Bacteria.
DR   eggNOG; COG4253; Bacteria.
DR   HOGENOM; CLU_004121_1_7_4; -.
DR   OrthoDB; 8590234at2; -.
DR   Proteomes; UP000008210; Chromosome 2.
DR   Gene3D; 2.30.110.50; -; 1.
DR   Gene3D; 4.10.220.110; -; 1.
DR   Gene3D; 3.55.50.10; Baseplate protein-like domains; 1.
DR   Gene3D; 2.40.50.230; Gp5 N-terminal domain; 1.
DR   InterPro; IPR006531; Gp5/Vgr_OB.
DR   InterPro; IPR028244; T6SS_Rhs_Vgr_dom.
DR   InterPro; IPR017847; T6SS_RhsGE_Vgr_subset.
DR   InterPro; IPR006533; T6SS_Vgr_RhsGE.
DR   InterPro; IPR037026; Vgr_OB-fold_dom_sf.
DR   InterPro; IPR018769; VgrG2_DUF2345.
DR   NCBIfam; TIGR01646; vgr_GE; 1.
DR   NCBIfam; TIGR03361; VI_Rhs_Vgr; 1.
DR   PANTHER; PTHR32305; -; 1.
DR   PANTHER; PTHR32305:SF15; PROTEIN RHSA-RELATED; 1.
DR   Pfam; PF10106; DUF2345; 1.
DR   Pfam; PF04717; Phage_base_V; 1.
DR   Pfam; PF05954; Phage_GPD; 1.
DR   Pfam; PF13296; T6SS_Vgr; 1.
DR   SUPFAM; SSF69255; gp5 N-terminal domain-like; 1.
DR   SUPFAM; SSF69349; Phage fibre proteins; 1.
DR   SUPFAM; SSF69279; Phage tail proteins; 2.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008210}.
FT   DOMAIN          418..482
FT                   /note="Gp5/Type VI secretion system Vgr protein OB-fold"
FT                   /evidence="ECO:0000259|Pfam:PF04717"
FT   DOMAIN          507..615
FT                   /note="Putative type VI secretion system Rhs element
FT                   associated Vgr"
FT                   /evidence="ECO:0000259|Pfam:PF13296"
FT   DOMAIN          641..786
FT                   /note="DUF2345"
FT                   /evidence="ECO:0000259|Pfam:PF10106"
SQ   SEQUENCE   816 AA;  90803 MW;  38261FFA66D7FFC7 CRC64;
     MGSRLPFSSR TVTVSGDGLP ELLGQPLLVF SRLSGTEGIN SLFEYELELK TPDDRNVLYG
     PAGDFDLEAM QGKELTVSIE LDGSGSGLDG GLGRGKREIT GIVTDVRGPY HENERIRYRL
     TLRPWFWLGT LTSTFKRFQN MNVLEIVEVV LSRYTFPVER RLSLIEYPKR QYQLQAGETD
     YQFVRRLLAE WGLNFHWEHT NGHHRMVLTD GNGAFQNIPS PAYHTINWYP SSDRVDEEHL
     HQFEVRDCLI TGSWAHGDYD YNQPRADLNV SVDDPRETSH ATYELYSWPG DYVQPKSGND
     ARKEGDMLAR INMERLRQHG VRVRGQGNVR AMAPGHTFTL KRFLRAKANR EYLIFATRLL
     IEDVGEFAGS DQQWRCEVEF EAQPTSEIFR PESVKKPYIG GHHIARVVGP ANQEIWSDDL
     GRVRCQFVWD RYGSFDENSS CWIRVTGFSS GGRFGNTHLP RIGQEVIVIY EGGDPDRPII
     IGPVNNRLNL PPWQLPSQHA LSGYQSKELF GEGRNQTLYD DTQGQQQVQV GSDYQNSLLA
     LGHIVRVRGW EGRKDKRGEG FELRTDAHGA LRAALGLLIT TFSRLNAEGN AMNVRDVVQL
     LEQAQGIAAT MGEKATEAQA QDGEQTDIAK LLEKQLEQIQ GGGELKEFTA PHLVSASPAG
     IVSTAAGSTH IASGGDTALT TGEHLSVTAG GGFFASVRKA LRMFAYEAGM KLVANMGDID
     LQALKNNINL LAKLKITLTA DEITIQARQK LLLAGGGSYL RLDGNIEHGT NGRFTVHAAS
     KLLTGPNSIP TELSTKQVCL ECLLKAARRN TGLLLR
//