ID Q0KB22_CUPNH Unreviewed; 1840 AA.
AC Q0KB22;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 94.
DE SubName: Full=DNA helicase {ECO:0000313|EMBL:CAJ92799.1};
GN OrderedLocusNames=H16_A1670 {ECO:0000313|EMBL:CAJ92799.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ92799.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ92799.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
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DR EMBL; AM260479; CAJ92799.1; -; Genomic_DNA.
DR STRING; 381666.H16_A1670; -.
DR KEGG; reh:H16_A1670; -.
DR eggNOG; COG0507; Bacteria.
DR eggNOG; COG1112; Bacteria.
DR eggNOG; COG3831; Bacteria.
DR HOGENOM; CLU_240138_0_0_4; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd07996; WGR_MMR_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 2.20.140.10; WGR domain; 1.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR036930; WGR_dom_sf.
DR InterPro; IPR008893; WGR_domain.
DR InterPro; IPR049809; YehF/YfeS-like_WGR.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR Pfam; PF05406; WGR; 1.
DR SMART; SM00773; WGR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF142921; WGR domain-like; 1.
DR PROSITE; PS51977; WGR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:CAJ92799.1};
KW Helicase {ECO:0000313|EMBL:CAJ92799.1};
KW Hydrolase {ECO:0000313|EMBL:CAJ92799.1};
KW Nucleotide-binding {ECO:0000313|EMBL:CAJ92799.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210}.
FT DOMAIN 1756..1840
FT /note="WGR"
FT /evidence="ECO:0000259|PROSITE:PS51977"
FT REGION 529..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1840 AA; 201947 MW; 31C9755C15C62368 CRC64;
MTDSTTHGTN TIPDMTGSGE PRMLRALIEA QAGAALPTDD VLVLVLPLFA QVATLHAQGR
VAALDRDSIL VDEDGALRLR RPDGEAPVMD IGAVHRVQPH PASGLNIVGA LQLGHADDGQ
RDQADLALQL DATAPVARPV YLPGPASWER LVGHHDEIGD IFLLGMVLAS LACGLDFADE
DDLRSFVAHR RNLFLLHERL HPIVAAVIVE MTEINRHDRA TDVAALATRL RTWRDQPLGL
DVERALAGTT GATPRRAAVL THLRDRLFDL SRRNRLLHFR PTAVSVNVTV ASVPLMLQIE
SVRPEHICTW GGPFAADLVA GKPVSLQRWL RFDDQPYLPA SLDRLIAETR RDRAEYGFSN
LRLVVAFLRW HNLKEAPDER IVTPLLWLPV ELVKRKGVRD QYVIQCAGGE AEFNPVLRHY
LSQLYDIRLD ETVDLGKISL EEIHAGILAQ IRRSEPSVEL RLVDKAAVRL VRQKALQRMQ
QFQRRKPGPA AARTGGWLPP YSYAQDDYRP LGRALFEHWV RPSELPQRFE AGAAPGAGPR
QPHMSGPAAA ESDERQGYVL EESEGHRYAW DLDLTQVTLA NFNYRKMSLV RDYAQLLDEP
GANPAFDRVF SIDPRDVETQ VPAPLAPAEQ WNVVGADATQ NAAVGLARSQ RSFIIQGPPG
TGKSQTITNL IADYAGRGKR VLFVCEKRAA LDVVFHRLKQ SGLDSLCSLI HDSQTDKKAF
IADLRACYEQ WIAQPHDGDA LAARRTQVVE ALAAYQQRID AFESAMASAP EALGDSVRAL
LRRVAALPAV PEAGPALRER LPALAAWDRQ RDLAHRVHRA MRERFGVDSL AAHPFARLSP
QLLADERAYG RAEQLCRDAE ALFDALDPLL DSTASLTGQD TALEQARAIA ADSQWLLDTG
LAAHLDLLDA ASPAQAALRE IRAELESRTQ ALADAQAATS NWQDKLSPGD TESALALARR
LEPSFARWLQ PAWWRLRGEL KRRYDFGKHA VHPGYGKVLE ALAAEHAASA ALAAADADSR
RRYGVGEMRA FLRALGELER RLQSGAGPRE LVAHLRQAVD PVAAARAEAG ARESLEKLAQ
RVRDGLALAA DARLGDIAEL LRDLREALDD LPDLLPLLRA VHAGDPACAA MLQWLDHAPV
QLEALVADEA LRRLTRENPV LARFGGAALA QAARAVAQGQ RELLALNAQV VRATRHRQFA
EHVRVSSLSA TMLDADGKAF KKQYATGRRE LEHEFGKSMR HRSIRDLCDD ETGLVINDLK
PIWLMSPLSV SDTLPLSPDL FDVVIFDEAS QIPTEEAVPA LSRARQVVVV GDEMQLPPTS
FFTAGGAEGD DEIVVEEEGE RIAINLDSDS LLNQAARNLP ATLLAWHYRS RHESLISFSN
AAFYDGRLVT IPDRLLEQAE DEAPALRSDQ EDAGIAGADA LLARPVSFHR LADGVYAERR
NAQEANYIAR TVRELLRRET GLSLGIVAFS EAQQGAIESA LEALAAEDAD FAMRLEREYV
REDDDQFNGL FVKNLENVQG DERDVIILSI CYAPGPDGKM LMNFGPINQR GGEKRLNVIF
SRARHRMAVV STIQAEAITN VHNDGAAALR AFLQFAQASA RGQFERAQSV LGALNPGARD
AFTREATPDS VRDALAEALR ARGHQVHANV GRSQFRCDLA IADPSGQGYA LAILLDAPSE
PVTDTAERYV FRPGVLRGFG WLVLDIPGKD WLDDRDAVLA RIEAMLADGE DRALDVEVEM
PVPLAKPAAA QDPASTGEAR TDAATASAAQ AELVRSLRFE QGTSRKFWRA SVRGAELSVT
YGRIGSTGQT SVKTFDSAER ARREADKLVA EKLRKGYIEA
//
