ID Q0KD15_CUPNH Unreviewed; 482 AA.
AC Q0KD15;
DT 03-OCT-2006, integrated into UniProtKB/TrEMBL.
DT 03-OCT-2006, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Transcriptional regulator, MocR family {ECO:0000313|EMBL:CAJ92106.1};
DE EC=2.6.1.- {ECO:0000313|EMBL:CAJ92106.1};
GN OrderedLocusNames=H16_A0963 {ECO:0000313|EMBL:CAJ92106.1};
OS Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
OS / H16 / Stanier 337) (Ralstonia eutropha).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=381666 {ECO:0000313|EMBL:CAJ92106.1, ECO:0000313|Proteomes:UP000008210};
RN [1] {ECO:0000313|EMBL:CAJ92106.1, ECO:0000313|Proteomes:UP000008210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier
RC 337 {ECO:0000313|Proteomes:UP000008210};
RX PubMed=16964242; DOI=10.1038/nbt1244;
RA Pohlmann A., Fricke W.F., Reinecke F., Kusian B., Liesegang H., Cramm R.,
RA Eitinger T., Ewering C., Potter M., Schwartz E., Strittmatter A., Voss I.,
RA Gottschalk G., Steinbuechel A., Friedrich B., Bowien B.;
RT "Genome sequence of the bioplastic-producing 'Knallgas' bacterium Ralstonia
RT eutropha H16.";
RL Nat. Biotechnol. 24:1257-1262(2006).
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
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DR EMBL; AM260479; CAJ92106.1; -; Genomic_DNA.
DR RefSeq; WP_011614811.1; NZ_CP039287.1.
DR AlphaFoldDB; Q0KD15; -.
DR STRING; 381666.H16_A0963; -.
DR GeneID; 57643064; -.
DR KEGG; reh:H16_A0963; -.
DR PATRIC; fig|381666.6.peg.1338; -.
DR eggNOG; COG1167; Bacteria.
DR HOGENOM; CLU_017584_0_1_4; -.
DR OrthoDB; 9804020at2; -.
DR Proteomes; UP000008210; Chromosome 1.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW Aminotransferase {ECO:0000313|EMBL:CAJ92106.1};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000008210};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:CAJ92106.1}.
FT DOMAIN 11..79
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 482 AA; 51881 MW; 3D6A4FE903D1F03E CRC64;
MELHLALDQA SDLTAQIVHQ IRDAIQGGRL EAGARMPPTR LLGTQLGVAR KTVTTAYERL
VAEGWLHARV GDGTYVAEGL ARPAMRMAAA PVLPPAVQRW MAVPTPFLDS GGGARSGFQP
GQADTTRFPH EAWSRCVRAA LAAERQRPPG VADPAGEMVL RQAIARHIAF TRGVQSMPTD
ILVTGGAQQG IDLLARLLLG PGAVVAMEDP GYPMARSLFQ GLGARVVPVP VDGEGLVVEA
LPNDATLVYV TPSHQSPLGV PMSLARRQAL LDWAALRHAV ILEDDYDSEF RYGGQALDAL
QTLDRHGRVV YLGTFSKTLV ANLRCGYLVV PPWLMPAARK VKHLMDWYTP TLIQQALARF
LSEGHLLRHI RRSHARHAQR RARLLARLHG DLSPWLEPLP AMAGFHLAAR LRVPVASEAL
VSTARLAGLA LATLDPCYAT PPATCAGLLL GFGAIDLLDI DPALDRLAMV LSALVPEPAH
AT
//
