ID Q0P8N6_CAMJE Unreviewed; 823 AA.
AC Q0P8N6;
DT 19-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 19-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Ntegral membrane protein {ECO:0000313|EMBL:CAL35485.1};
GN OrderedLocusNames=Cj1373 {ECO:0000313|EMBL:CAL35485.1};
OS Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC
OS 11168).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Campylobacteraceae; Campylobacter.
OX NCBI_TaxID=192222 {ECO:0000313|EMBL:CAL35485.1, ECO:0000313|Proteomes:UP000000799};
RN [1] {ECO:0000313|EMBL:CAL35485.1, ECO:0000313|Proteomes:UP000000799}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700819 / NCTC 11168 {ECO:0000313|Proteomes:UP000000799};
RX PubMed=10688204; DOI=10.1038/35001088;
RA Parkhill J., Wren B.W., Mungall K., Ketley J.M., Churcher C., Basham D.,
RA Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K.,
RA Karlyshev A., Moule S., Pallen M.J., Penn C.W., Quail M., Rajandream M.A.,
RA Rutherford K.M., VanVliet A., Whitehead S., Barrell B.G.;
RT "The genome sequence of the food-borne pathogen Campylobacter jejuni
RT reveals hypervariable sequences.";
RL Nature 403:665-668(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; AL111168; CAL35485.1; -; Genomic_DNA.
DR PIR; B81282; B81282.
DR RefSeq; WP_002858465.1; NZ_SZUC01000003.1.
DR RefSeq; YP_002344761.1; NC_002163.1.
DR AlphaFoldDB; Q0P8N6; -.
DR STRING; 192222.Cj1373; -.
DR PaxDb; 192222-Cj1373; -.
DR EnsemblBacteria; CAL35485; CAL35485; Cj1373.
DR GeneID; 905666; -.
DR KEGG; cje:Cj1373; -.
DR PATRIC; fig|192222.6.peg.1354; -.
DR eggNOG; COG1033; Bacteria.
DR HOGENOM; CLU_008861_3_1_7; -.
DR OrthoDB; 5429313at2; -.
DR Proteomes; UP000000799; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000799};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 249..268
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..452
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 655..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 680..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 706..728
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..771
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 777..806
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 240..402
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 678..804
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 823 AA; 93510 MW; AB49134CD015DC9F CRC64;
MFAKLLKFFI SRPKSTFFGT LFICLFLSFF AFKLSVDASA ESLLLEDDAD LKTFREISKH
YKSDNFLLLA FKPYDEKPFS NENLAKLKKL HEELEKAPLV ERVFSIINAP LLQSSQNTDL
KELLKNIPNI ESQDINRTKA QNEILNSPFY KNNIISKDGK VTGLIIYLKP DTVYNNLIEK
RDLATDEKEK DQIRLAIKEH QDKQKVITKQ SLDTIKSIVR NYEKNKDTLY LGGVSMIADD
MIAYIKSDLV LYGVSLVFLL GLALYYFFRS WRFVFLPLFI CFISLSAASG VFALLNFQIT
VISSNYVALV LIITLSVVVH LITHFIESTQ NHPKAKVERI VLETLLAKAN PSLYAIVTTM
IGFFSLILSN IEPIIKLGIM MSIGIGLALI FSYLFLASIL VLLKPKNYHK KEFKFNLLAF
CAKTALDPKK RRMIYEISVL AIILALIGIS KLRVENSFVN YFKDGSEIKK GLLVIDKNLG
GTLPLEVIIR FPNNKNDQNA SDTLDSFESE FENLATQETY WFDSKKTRIA KKVHEFLENK
EFVGSVLSLN SLLTLGKNIN DGKELDDFAL AFLNENLPAK FKQDLLSPFV SIENNELRFS
MRIVDSDPNL RRNEFLIDLK KQLNELVKND GVEVQITGIM VLYNNMLQSL FSSQFDTLIF
VILAIFILFI IVFRDLKFSV AAILVNVIPL SVVFALMGLL GIPLDMMSIT IAAIAIGIGV
DDAIHYIYRF REEIKNKSLE EAIMISHLSI GSALYYTTIS IVLGFSVMMS SNFIPTIYFG
ILTVFVMILL LSGSLFLLPS FLITIYSKKT KFPNQHKEHI LKQ
//
