ID   Q0RNQ8_FRAAA            Unreviewed;       536 AA.
AC   Q0RNQ8;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   27-MAR-2024, entry version 93.
DE   SubName: Full=Putative DNA-directed DNA polymerase {ECO:0000313|EMBL:CAJ60828.1};
DE            EC=2.7.7.7 {ECO:0000313|EMBL:CAJ60828.1};
GN   OrderedLocusNames=FRAAL2179 {ECO:0000313|EMBL:CAJ60828.1};
OS   Frankia alni (strain DSM 45986 / CECT 9034 / ACN14a).
OC   Bacteria; Actinomycetota; Actinomycetes; Frankiales; Frankiaceae; Frankia.
OX   NCBI_TaxID=326424 {ECO:0000313|EMBL:CAJ60828.1, ECO:0000313|Proteomes:UP000000657};
RN   [1] {ECO:0000313|EMBL:CAJ60828.1, ECO:0000313|Proteomes:UP000000657}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ACN14a {ECO:0000313|Proteomes:UP000000657};
RX   PubMed=17151343; DOI=10.1101/gr.5798407;
RA   Normand P., Lapierre P., Tisa L.S., Gogarten J.P., Alloisio N.,
RA   Bagnarol E., Bassi C.A., Berry A.M., Bickhart D.M., Choisne N., Couloux A.,
RA   Cournoyer B., Cruveiller S., Daubin V., Demange N., Francino M.P.,
RA   Goltsman E., Huang Y., Kopp O.R., Labarre L., Lapidus A., Lavire C.,
RA   Marechal J., Martinez M., Mastronunzio J.E., Mullin B.C., Niemann J.,
RA   Pujic P., Rawnsley T., Rouy Z., Schenowitz C., Sellstedt A., Tavares F.,
RA   Tomkins J.P., Vallenet D., Valverde C., Wall L.G., Wang Y., Medigue C.,
RA   Benson D.R.;
RT   "Genome characteristics of facultatively symbiotic Frankia sp. strains
RT   reflect host range and host plant biogeography.";
RL   Genome Res. 17:7-15(2007).
CC   -!- FUNCTION: Poorly processive, error-prone DNA polymerase involved in
CC       untargeted mutagenesis. Copies undamaged DNA at stalled replication
CC       forks, which arise in vivo from mismatched or misaligned primer ends.
CC       These misaligned primers can be extended by PolIV. Exhibits no 3'-5'
CC       exonuclease (proofreading) activity. May be involved in translesional
CC       synthesis, in conjunction with the beta clamp from PolIII.
CC       {ECO:0000256|ARBA:ARBA00025589}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC       {ECO:0000256|ARBA:ARBA00010945}.
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DR   EMBL; CT573213; CAJ60828.1; -; Genomic_DNA.
DR   RefSeq; WP_011603344.1; NC_008278.1.
DR   AlphaFoldDB; Q0RNQ8; -.
DR   STRING; 326424.FRAAL2179; -.
DR   KEGG; fal:FRAAL2179; -.
DR   eggNOG; COG0389; Bacteria.
DR   HOGENOM; CLU_026357_0_0_11; -.
DR   OrthoDB; 5244088at2; -.
DR   Proteomes; UP000000657; Chromosome.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   CDD; cd03468; PolY_like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR35369:SF2; BLR3025 PROTEIN; 1.
DR   PANTHER; PTHR35369; BLR3025 PROTEIN-RELATED; 1.
DR   Pfam; PF00817; IMS; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50173; UMUC; 1.
PE   3: Inferred from homology;
KW   DNA-directed DNA polymerase {ECO:0000313|EMBL:CAJ60828.1};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:CAJ60828.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000657};
KW   Transferase {ECO:0000313|EMBL:CAJ60828.1}.
FT   DOMAIN          23..159
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
SQ   SEQUENCE   536 AA;  55500 MW;  2EF604E8A90DB5DD CRC64;
     MPVRMLAVHY PDWPAVAAGV AADQPGAVLA AGRVVAATPA ARRAGIRPGL RRREAQARCP
     EITLVPDDPG RAARVFEPLV AAVESVAPGV EVRGPGDCVV PVRGVARYFG GVEAALAEVR
     RALTAAWPAA VRSAGAVGPA PRCGLGVADG PFAAGIAARG EAVVPLGGTA AFLAPHPVDL
     LGDAELVDLL RRLGLVTLGS FAALPAADVA ARFGPPGDWA HRLARGEDPR PVTPREHPVD
     LGVVTAFDPP AERVEQAAFA ARRLAEQAHD RLRDHGLACT GIRMEAETGH GEHHVRTWRH
     DGPLAAAAIT DRVRWQLDGW LAGSASAGDE VAHAAMPTRP RGAAGSGPTA GVVRLRIEPV
     GLVPAAGRQL GLWGEPGAAA ARVGRALTRV QGLLGPDAVL TAVVGGGRDP GDRIRLVPWG
     EPRVATGLDR PWPGTLPAPA PTLVHRPPLV ASVLDDAGEP VGVSARCTVT APPARLAIGA
     GSPMPVTGWA GPWPVDERWW DADARRRARF QISVAEGGAY LLAVAGGRWW VEASYD
//