ID   Q0SA48_RHOJR            Unreviewed;       195 AA.
AC   Q0SA48;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   27-MAR-2024, entry version 101.
DE   SubName: Full=Probable aminoglycoside N(6prime)-acetyltransferase {ECO:0000313|EMBL:ABG95588.1};
DE            EC=2.3.1.82 {ECO:0000313|EMBL:ABG95588.1};
GN   OrderedLocusNames=RHA1_ro03788 {ECO:0000313|EMBL:ABG95588.1};
OS   Rhodococcus jostii (strain RHA1).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Rhodococcus.
OX   NCBI_TaxID=101510 {ECO:0000313|EMBL:ABG95588.1, ECO:0000313|Proteomes:UP000008710};
RN   [1] {ECO:0000313|Proteomes:UP000008710}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RHA1 {ECO:0000313|Proteomes:UP000008710};
RX   PubMed=17030794; DOI=10.1073/pnas.0607048103;
RA   McLeod M.P., Warren R.L., Hsiao W.W.L., Araki N., Myhre M., Fernandes C.,
RA   Miyazawa D., Wong W., Lillquist A.L., Wang D., Dosanjh M., Hara H.,
RA   Petrescu A., Morin R.D., Yang G., Stott J.M., Schein J.E., Shin H.,
RA   Smailus D., Siddiqui A.S., Marra M.A., Jones S.J.M., Holt R.,
RA   Brinkman F.S.L., Miyauchi K., Fukuda M., Davies J.E., Mohn W.W.,
RA   Eltis L.D.;
RT   "The complete genome of Rhodococcus sp. RHA1 provides insights into a
RT   catabolic powerhouse.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15582-15587(2006).
CC   -!- SIMILARITY: Belongs to the lysine N-acyltransferase MbtK family.
CC       {ECO:0000256|ARBA:ARBA00009893}.
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DR   EMBL; CP000431; ABG95588.1; -; Genomic_DNA.
DR   RefSeq; WP_011596349.1; NC_008268.1.
DR   AlphaFoldDB; Q0SA48; -.
DR   KEGG; rha:RHA1_ro03788; -.
DR   PATRIC; fig|101510.16.peg.3813; -.
DR   eggNOG; COG1670; Bacteria.
DR   HOGENOM; CLU_013985_12_2_11; -.
DR   OrthoDB; 9814648at2; -.
DR   Proteomes; UP000008710; Chromosome.
DR   GO; GO:0047663; F:aminoglycoside 6'-N-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   CDD; cd04301; NAT_SF; 1.
DR   Gene3D; 3.40.630.30; -; 1.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   PANTHER; PTHR31438; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR   PANTHER; PTHR31438:SF1; LYSINE N-ACYLTRANSFERASE C17G9.06C-RELATED; 1.
DR   Pfam; PF13523; Acetyltransf_8; 1.
DR   SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000313|EMBL:ABG95588.1};
KW   Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008710};
KW   Transferase {ECO:0000313|EMBL:ABG95588.1}.
FT   DOMAIN          8..183
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS51186"
SQ   SEQUENCE   195 AA;  21672 MW;  385777F77F73F16F CRC64;
     MSADAVTFEF VRTTREFFPQ LQRWLREPHV ARFWNHDTAD ADIERDFGGS IDGTEPCEDF
     LVLRGGLPFG FIQRYRIADY PEDLALLAAL VEIPPGSISI DYYVGDPQHT GRGLGTAMIS
     AFVAKCRADL PDATAIVVPV VVPNRASWRA LEKAGFRRVG EGYLPPDNPI DDGAHYISRL
     DLDGCRPVQP VSPDR
//