ID UGPE_ECOL5 Reviewed; 281 AA.
AC Q0TC09;
DT 26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpE {ECO:0000250|UniProtKB:P10906};
GN Name=ugpE; OrderedLocusNames=ECP_3544;
OS Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=362663;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=536 / UPEC;
RX PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT "Role of pathogenicity island-associated integrases in the genome
RT plasticity of uropathogenic Escherichia coli strain 536.";
RL Mol. Microbiol. 61:584-595(2006).
CC -!- FUNCTION: Part of the ABC transporter complex UgpBAEC involved in sn-
CC glycerol-3-phosphate (G3P) import. Probably responsible for the
CC translocation of the substrate across the membrane.
CC {ECO:0000250|UniProtKB:P10906}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC (UgpB). {ECO:0000250|UniProtKB:P10906}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000250|UniProtKB:P10906}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. UgpAE subfamily. {ECO:0000305}.
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DR EMBL; CP000247; ABG71520.1; -; Genomic_DNA.
DR RefSeq; WP_000572183.1; NC_008253.1.
DR AlphaFoldDB; Q0TC09; -.
DR SMR; Q0TC09; -.
DR GeneID; 66506595; -.
DR KEGG; ecp:ECP_3544; -.
DR HOGENOM; CLU_016047_1_1_6; -.
DR Proteomes; UP000009182; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; MetI-like; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR43744; ABC TRANSPORTER PERMEASE PROTEIN MG189-RELATED-RELATED; 1.
DR PANTHER; PTHR43744:SF8; SN-GLYCEROL-3-PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN UGPE; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; MetI-like; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..281
FT /note="sn-glycerol-3-phosphate transport system permease
FT protein UgpE"
FT /id="PRO_0000292677"
FT TRANSMEM 16..36
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 77..268
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 281 AA; 31530 MW; 2CAF3F10CE4CF5A6 CRC64;
MIENRPWLTI FSHTMLILGI AVILFPLYVA FVAATLDKQE VYAAPMTLIP GTHLLENIHN
IWVNGVGTNS APFWRMLLNS FVMAFSITLG KITVSMLSAF AIVWFRFPLR NLFFWMIFIT
LMLPVEVRIF PTVEVIANLK MLDSYAGLTL PLMASATATF LFRQFFMTLP DELVEAARID
GASPMRFFCD IVFPLSKTNL AALFVITFIY GWNQYLWPLL IITDVDLGTT VAGIKGMIAT
GEGTTEWNSV MAAMLLTLIP PVVIVLVMQR AFVRGLVDSE K
//
