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Database: UniProt
Entry: Q0U397
LinkDB: Q0U397
Original site: Q0U397 
ID   MRH4_PHANO              Reviewed;         658 AA.
AC   Q0U397;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 2.
DT   16-OCT-2019, entry version 64.
DE   RecName: Full=ATP-dependent RNA helicase MRH4, mitochondrial;
DE            EC=3.6.4.13;
DE   Flags: Precursor;
GN   Name=MRH4; ORFNames=SNOG_13767;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
OS   (Glume blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
OC   Phaeosphaeriaceae; Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing
RT   and EST analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: ATP-binding RNA helicase involved in mitochondrial RNA
CC       metabolism. Required for maintenance of mitochondrial DNA (By
CC       similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. MRH4
CC       subfamily. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAT78791.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
DR   EMBL; CH445352; EAT78791.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_001803973.1; XM_001803921.1.
DR   STRING; 13684.SNOT_13767; -.
DR   GeneID; 5980895; -.
DR   KEGG; pno:SNOG_13767; -.
DR   InParanoid; Q0U397; -.
DR   KO; K17678; -.
DR   OrthoDB; 1223767at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030490; P:maturation of SSU-rRNA; IBA:GO_Central.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase; Mitochondrion;
KW   Nucleotide-binding; Reference proteome; RNA-binding; Transit peptide.
FT   TRANSIT       1     32       Mitochondrion. {ECO:0000255}.
FT   CHAIN        33    658       ATP-dependent RNA helicase MRH4,
FT                                mitochondrial.
FT                                /FTId=PRO_0000256055.
FT   DOMAIN      233    449       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      490    658       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     246    253       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       182    214       Q motif.
FT   MOTIF       396    399       DEAD box.
FT   COMPBIAS     37    150       Arg-rich.
SQ   SEQUENCE   658 AA;  73123 MW;  15DB619EBA80ACCF CRC64;
     MLRQVTRACP FCEVRSLLGQ APRSLQPQTR LYTQVQREAQ RERGSRDSNT PSRPRDRRTP
     ETDAFPPSSD RGSRGRSPRG RDDRRPSRMI LSDAVSRPPQ SDQRPARRPQ EPFGHLNRTR
     APPSLERERE RRESHFERPK RNDDGKRRTR AEPYHALKMQ RSLHEVPYGN RTTIKRKMEL
     YDSFDKMPLL DTVQAAIKDA LPALEYRSPT PAQSVAVPAL LGLEAKKRTK ATSTKKGGPE
     AFLLAAETGS GKTLAYLLPT LDAIKKAEQQ EKEDAEAQAQ KDADEAAAKA QDKRTDIFAA
     EEPEVNKAVD PARPRAIILV PSAELVAQVG AVAKSLSHTV KFRAAPISAK MSATVIRNQL
     FNEKGVDVVI STPPLLASIA ESNPNILARV THLICDEADS LFDRSFKPST TEILERATPS
     LKQLILCSAT IPKYLDKYLA DRFPDMNRLV TPNLHAIPRR VQLGVVDVNK DPYHGNKNLA
     CADTIWQIGR STGEYDPAEG KEAVPTKRIL VFVNEREDTE KVAQYLMSKG IDALAFHRDT
     DPSRQAKTLA SFTGSDTSTA IKSSPDAPPK PELASKRTLA NTKVIVTTDL GSRGIDTVSV
     RHVILYDVPH TTIDFIHRLG RTGRMGRRGR GIVLLGPGDR ADVVKEVREA MYRGEALI
//
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