ID Q0UGN3_PHANO Unreviewed; 5149 AA.
AC Q0UGN3;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-FEB-2008, sequence version 2.
DT 27-MAR-2024, entry version 104.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=SNOG_09081 {ECO:0000313|EMBL:EAT83273.2};
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614 {ECO:0000313|EMBL:EAT83273.2, ECO:0000313|Proteomes:UP000001055};
RN [1] {ECO:0000313|Proteomes:UP000001055}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173
RC {ECO:0000313|Proteomes:UP000001055};
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G., Solomon P.S., Tan K.C., Schoch C.L., Spatafora J.W.,
RA Crous P.W., Kodira C., Birren B.W., Galagan J.E., Torriani S.F.,
RA McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- SIMILARITY: Belongs to the NRP synthetase family.
CC {ECO:0000256|ARBA:ARBA00029454}.
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DR EMBL; CH445338; EAT83273.2; -; Genomic_DNA.
DR RefSeq; XP_001799383.1; XM_001799331.1.
DR STRING; 321614.Q0UGN3; -.
DR EnsemblFungi; SNOT_09081; SNOT_09081; SNOG_09081.
DR GeneID; 5976284; -.
DR KEGG; pno:SNOG_09081; -.
DR VEuPathDB; FungiDB:JI435_090810; -.
DR eggNOG; KOG1178; Eukaryota.
DR HOGENOM; CLU_000022_60_0_1; -.
DR InParanoid; Q0UGN3; -.
DR OrthoDB; 2787863at2759; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IBA:GO_Central.
DR GO; GO:0043041; P:amino acid activation for nonribosomal peptide biosynthetic process; IBA:GO_Central.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IBA:GO_Central.
DR CDD; cd05918; A_NRPS_SidN3_like; 4.
DR CDD; cd19542; CT_NRPS-like; 1.
DR CDD; cd19534; E_NRPS; 1.
DR CDD; cd19545; FUM14_C_NRPS-like; 2.
DR Gene3D; 3.30.300.30; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 4.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 6.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 4.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 5.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 4.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 4.
DR Pfam; PF00668; Condensation; 6.
DR Pfam; PF00550; PP-binding; 4.
DR SMART; SM00823; PKS_PP; 4.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 4.
DR SUPFAM; SSF47336; ACP-like; 4.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 11.
DR PROSITE; PS00455; AMP_BINDING; 4.
DR PROSITE; PS50075; CARRIER; 4.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000001055}.
FT DOMAIN 563..639
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2109..2185
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3165..3241
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4230..4304
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 5149 AA; 568420 MW; 038E725A08A7007A CRC64;
MGSVSGIDAV WAWNEHVPTF IDETVSDLVQ KQVKLRPDAL AVDAHDGTWT YAELDAAANR
VAHYLSDLGI GPEDVVPLCF EKSRWAIVAI LSVLKTGAAF VFLDPSHPVD RRQYITSEVE
AKVIICSPSQ IHLYESECPP TFMLSEDSLE SLPERDVARK TSAAPSNLLY VIFTSGSTGN
PKGCLIENRA FLSGSLRHAE RAAIDHTTRI LQLASYSFDV SMLEILTALV HGSCICTPDM
ALMANGPACI VNEYKITWAF MTPSLVKLMA PNMVPTLKTL ALGGEPLSKI DVETWASELQ
LINGYGPSEC SVAATGNTEM TPDTDPANIG FPVGGICWIV DAEDHDLLLA PGEVGELLIE
GPILARGYLK NKEKTDEVFV ERPAWGPTTK TGENRRFYKT GDLAKYLPDG SIYFVGRKDT
QVKLRGLRIE LGEIEHNIGT HPQVRHQMVI LPKKGSFANR LVALVSLRDF LVESYEAVES
TVYLHEDLHS DEIKTHLESI RQGLASKVPE YMVPETWIVL ERFPLLLSGK LNRSLVSKWV
AEANEDLYRQ VVGIDFEEVV DADTLGGSEE KLRDIIAAVL NLPPSSVSLS KSFLSLGGDS
ITAMQVMSRC RSAGLAVSVR DILRSKSVTE LSLSVKSAKE TSYSTDEVFD VAFELSPVQR
MYFDIAPTEI DDARQTRFNQ SFFLRIQQPV SQLNVAKALQ AVVTQHSMLR VRFVQDGVKW
MQIIPSKVED TFSFATFNID SVNDAYPIMA ETQTSLDTRN GPIFAVVLFN TSTDGQYLFL
VAHHVMIDLV SWRVILRDIE EFLTIGSLTA AKPIPFQNWL SLQAEHARAT NISSVLPYDI
PAPDFDYWNM SSKPNRMCDT KEAVIKLDLT QTKELLEGSC HATYNTEPID VLLASLVYSF
SQTFSDRAVP ALFREGHGRE PWDDDLDISG TVGWFTTMYP LHVEMQQRFD ILEVIKRAKD
VRHSVPANGR PYFASRYLND AGIEKFGGHD HVELSFDYLG LYQQMERADA LLTQVPGYQA
IFEDVGKESP RFALVEITAE VLQGQMQLLF VFNKQMKHQG RIHLWMSNAQ ACIADALAQL
QGHEEERTLS DFPLLKLSYE DLDLLVSTKM PEIGISDIAR VESVYPSSPM QHGLLISQVR
GGSQGAYEYN HTLKVETRND SDVLDIGALE SAWAQVVQRH SSLRTVFIES VSHAGLYDQV
VLKAIDPSIH SQECSESEVE QVFDSRGKLA FRPGEALHRF TICHVSSTTA ICKLEINHAI
IDGSSIANIM GDFILAYDGR MSNRPGFAFQ DYIKHVLDRP LSLATEFWRQ YLVDVNPSFF
PLMAHWEDAV DPARKLETAT IDVGISAAEL MAFCDTKNAT LVNIFQLAWG LVLKQHIGTE
DVCFGYLSSG RDAPLEGIEQ GVGAFITMLV SRMVLDDSLS MNDALERVAD DLLKTLPNQH
CGLAEIHHAL KLGSQPLFNT IISFHRETDH ELITDSSITV EAIKGYDPTE YALSLDVGVT
ESKVDVTLQF WTSEFTAAQA QNIGATLSEA VKAILYHSTK RIGEVDLVSS LHIQQMRNIT
AVYPQYVSEC VHHAIEAQAY ATPEAEAICS YQGSWTYKEL NEQANRLAHH LASLGVGPET
IVPYVFEKSA WAIVSILAIL KAGAAGVAFD PNHPIERIES LIEQTESFII LTSTQNAALF
ANTANLEAVI VVDKDFIFEL PVATRPACTT VRPENACFVV FTSGTTGKPK GIVLEHRNMR
TCSTSMGPVL DFGPHTRALQ FAAYNFDVSL QDIVTTLQFG GAVCVISDEE RMNDLAGGIN
RTQANWADLT ATVSGMLNPK DVPSMRRLNN GGEPLNRDVI ETWADHVQLH NLYGPAETTV
NQTGSIRLSR TSPASNIGPA FGTHVWIAND QDHNRLVPMG CAGEILIEGP LLARGYLKEP
EKTAAAFIEN PAWVADFPDA NALLPRRFYK SGDIGCLNTD GSITIVGRRD AQVKINGQRV
ELDEIMYQAQ LLLPEGYSIV VDAVAIEEHT KSKTIVGFVT NPAFAKHRKA AEASTFEINE
DLRHILKDLQ SSLAKVLPFY MIPSLFVPVF NIPYTTSGKL ARPVLRQIVA SFTKTQVSHY
MLRSASTDQP RTTMEQILQT LFAEILSLDP ATINRDDNFF GLGGDSVGGM KMVAAARKHN
FAIRVADIFK YPILSELAEV VEATQEYAPQ ATEVEAFALV EEQAKTSILA EAATQCNTDI
ADIEDIYPTS ALQEGLRKKG AYIAQKVFRL PQDFDLSRFQ DAWKTVIERE AILRTRIVSS
SVGNLQVVTK APTIWQTATD LESFLAKDQA TAFKYGDPLM RLASIGQEYF VWTAHHAIYD
GWSLALLFEK IGQAYNGAEV SSSTPYRNFI GRLNETSRSA NVDFWKNYPE VGLGYSAAAK
KTIALQSSAP QLSSTILPST IKRAAWALTI ATYADSEDVV FAQTLAGRNL ALEGIDNMMG
PTITTVPVRV SVPKEGITVK DLLQSVQDQS VATIEYEHFG LQNIRDISKE SRTTIDSITN
LFVIQPAEDS SDTVLDLETV PRAEENFDNF PLVVLCNLGK DNDFTLEAIY DESIIPTEQM
TRMLHQYEHF VKELSLDIER PVEKISLLNS YDFKDITTWN TELPAGIDAR IPDLIAQNVA
TRPNAQAVCA WDGSLTYREL DLITSKLANH LTTLGVGPEV QVGLCFDKSM WNIVSMLAVM
RTGGVCVQFL PNYPMPRMLS ILEDIEADVV LVSPQHAGLF ERVVSKVLAI DQAFVDSFPA
SYSKFEAPEY SPDNAAFIVF TSGSTGKPKG VIIEHRGFCT MAHYQLPQIL LEPDSRVLQF
ATHTFDICLF ESFAPLVKGA CVCVPSEYDR MNNLVSAINS LNVDWIIMVS TVADTFHPDQ
VPGLKSIILG GEPLRADIHA RWAPRVNLFN DYGPAECSIL AVMTHSHLET PCSMIGKAQG
GRSWVVDKTD HNRLVPVGCV GELLIEGPLL ARGYLKNPTK TNESYIYDPT WATQISPNPS
RLYKTGDLVR YVQDGNMLCL GRKDTQIKIR GLRVELGEIE HHVKTSAFGT QKQAVEKILL
EGDVDKAALA AFVVPSVEDV DNGNEEVMAL TSALHGKFHQ LKEHIAQSLS SYMVPSLYIP
LRKMPETQTN KIDRNSLKRI GASLTLEQIQ QYSLGEEEDL ANKRVPSTPM ELALQGLWAE
LLRIDTTSIG ADDSFFSKGG DSIKAMRLTS LARSNGINLI VADIFKNPVL CDMAKCASAE
TQEAIASIEP FSLVSSEENL IEDAAAVCNV SKDDIEDLYP CTPLQEALME LATQQQGAYT
AQRVFKIAAG IDIDCFKSAW SQLVDLHPIL RTRIILSKSS GAIQVVLRNG LEWQPEIALP
DYLAQDKATF VKYGSPLARY ALDSEHSHFV WTVHHALYDG HTAINLMEQL ENLYNKQQID
AAPGYNRFIK MITEVDAKEC AAFWKKQLGQ ATANSFPTIL DATYQPTPDS EVTRTIAISR
DTSKGFMLST ILRAAWAIVT SRLLGSEDVA FAATNSGRNA AVQDIENIVG PTITTVPIQL
QVNSAASIAS FLATVQQQST EMIPYEHAGL QSVYAMAGQK QNLKNLLVIQ QPFGEIKESS
IMEEVLDKGL LRGFHIYAAV VECIVTGDDS VDVELQFDSN IIQCASATTI LEQFECVIQQ
LVNASETTSL KDVNMMTPAH YQQIIEWNSR VDIQEVDDCV HNIFREQARI RPDATAVTSW
DGEITYKQLD ELSDKLASHL VEKGVKPEYL MPMCFDKSVY TVITMMATLK AGGATVHLGK
NSPIDRMAEI ISQTGAAFVL TDNIHAHKFD GVIETVIVDQ KLLDSLTSTA SLPTVSPNDP
AFVLFTSGST GKPKGVVGEH ASMCTSSRAH GTNRKVGPWT RLFQFAAYTF DVSIADIFTT
LQRGGCICVP SEDERINDIP GAIRRMNCDY AFLTPTVAAM LEPKDVPTLK KLILGGEAAA
RDTVRRWAPA VDLIFSYGMT ECGIHCVDAD PKSPETDPAD VGRPSGCHMW IVDAEDHNKL
APLGATGELV IEGKVVSRGY LGDEAKTAAA FVVDPTWSQG SGKTRRMYKT GDLFKYGPEG
QLLCCGRKDF QVKHHGQRIE LAEIEANILA DPRVNQAVVL LPKAGHLQKK LVAVLSLESL
SQTLSPETQL NLVTGLDKGL ADVQTAAVRS YVATKVPDYM VPAVWIVVQA MPLTPNNKMD
RVTVTKWLVE MEQETYEMVV GSDEEEEGGA PATEQQKRVH DILSNVLGLP KVNMNRSFLD
LGGDSIAAMN LRSKCQASGI LLSVKDILVC ESISHLVLEA KFEGTEEEED IVGKPFALTA
WQHVLLEQEV EAQKIMLPLA TRTTVPKLVR AIEAIMQQHP MLRARFQRNA EATWSQVITK
ELASSYKFEA QTRSTTTDVK AFLAAMQPGL NIETGPLFSV HLFDLTEDST QQALALTIHP
VIADAASVRI ILQDIRELLQ GNMMSIHSDM SFQSSISVDT SAAAIGASAV DLNRWGIEDK
RMLTRNLVEK SITLPSGITS SLIGTANKAL STQPIDILVA VLSKVWSTIF GRTASMAVKD
GSRTNRVVGQ FDRVRQLHET TTDEFVQLLS EIKDDRIFEC MSSTLTAGLP EVVEVLIESI
DHNSFSSGEY LHRSSVHIPA VLAVSAAVAN GEIKIRFTHS SDLSQQETLA TFIGVVEQTI
PTVARTLSDM SRKPTLADFP LLDMEYPDLP VLEKTFANIN VSYSNVEAIV PCTPLQQRML
NAQTEVHGAW QSDSAHKITS GGHLDNDIVR IQQAWQQVIA RHEAMRTIFI PSVSRSFGSD
QLILKSYQPL VDVIECDEAN IQRIIANHHT VVHSSYRPHV GFTLFRTPSA LYSKIELSHA
MHDGMSIRNI FHDLVLAYQE SLPSGPAAGF REYVNWAAHQ DLSASEAFWD EYLRDVSPCH
IPRKVDETIE KRSNVLTPVQ IQIDLASDVI NTMCRKYKVT SATLFQAAWV LVLRTLAEQD
DVLFGYLTAN RELNIPGWAC RINVKSDDKI TEVLKQTHDS FLSTLEHQHS FVSSASAKES
LDGERPFNTC MSIEYATGGI QASSATDAAV QTPSLSFESV HESRAPEFEV ALGVLVGDKN
VKVQLGYHAG VMEESMMDRL ARMYGDVVRE MVEGDGLAGE VRDLKALAA
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