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Database: UniProt
Entry: Q0UK12
LinkDB: Q0UK12
Original site: Q0UK12 
ID   RRP3_PHANO              Reviewed;         546 AA.
AC   Q0UK12;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 2.
DT   16-OCT-2019, entry version 76.
DE   RecName: Full=ATP-dependent rRNA helicase RRP3 {ECO:0000305};
DE            EC=3.6.4.13 {ECO:0000250|UniProtKB:P38712};
GN   Name=RRP3 {ECO:0000250|UniProtKB:P38712}; ORFNames=SNOG_07902;
OS   Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)
OS   (Glume blotch fungus) (Parastagonospora nodorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae;
OC   Phaeosphaeriaceae; Parastagonospora.
OX   NCBI_TaxID=321614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX   PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA   Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA   Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA   Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT   "Dothideomycete-plant interactions illuminated by genome sequencing
RT   and EST analysis of the wheat pathogen Stagonospora nodorum.";
RL   Plant Cell 19:3347-3368(2007).
CC   -!- FUNCTION: ATP-dependent rRNA helicase required for pre-ribosomal
CC       RNA processing. Involved in the maturation of the 35S-pre-rRNA and
CC       to its cleavage to mature 18S rRNA.
CC       {ECO:0000250|UniProtKB:P38712}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000250|UniProtKB:P38712};
CC   -!- SUBUNIT: Interacts with the SSU processome.
CC       {ECO:0000250|UniProtKB:P38712}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The Q motif is unique to and characteristic of the DEAD
CC       box family of RNA helicases and controls ATP binding and
CC       hydrolysis. {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the DEAD box helicase family. DDX47/RRP3
CC       subfamily. {ECO:0000305}.
DR   EMBL; CH445336; EAT84178.2; -; Genomic_DNA.
DR   RefSeq; XP_001798228.1; XM_001798176.1.
DR   SMR; Q0UK12; -.
DR   STRING; 13684.SNOT_07902; -.
DR   PRIDE; Q0UK12; -.
DR   EnsemblFungi; SNOT_07902; SNOT_07902; SNOG_07902.
DR   GeneID; 5975126; -.
DR   KEGG; pno:SNOG_07902; -.
DR   InParanoid; Q0UK12; -.
DR   KO; K14777; -.
DR   OrthoDB; 744428at2759; -.
DR   Proteomes; UP000001055; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000629; RNA-helicase_DEAD-box_CS.
DR   InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00039; DEAD_ATP_HELICASE; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS51195; Q_MOTIF; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Helicase; Hydrolase;
KW   Nucleotide-binding; Nucleus; Reference proteome; Ribosome biogenesis;
KW   RNA-binding; rRNA processing.
FT   CHAIN         1    546       ATP-dependent rRNA helicase RRP3.
FT                                /FTId=PRO_0000282698.
FT   DOMAIN      146    318       Helicase ATP-binding.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00541}.
FT   DOMAIN      342    490       Helicase C-terminal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00542}.
FT   NP_BIND     159    166       ATP. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00541}.
FT   MOTIF       115    143       Q motif. {ECO:0000305}.
FT   MOTIF       265    268       DEAD box. {ECO:0000305}.
SQ   SEQUENCE   546 AA;  59515 MW;  8B46A37462C0F70D CRC64;
     MSDFKRRKLE GGKSAIDAAR ERKALKKASA PLKKSHAKPA PSNKPTAKRP PPPSPPQSQS
     EEDEDEFGGF SGEEEEDVSR AKMTNGSTAK ADAEAEQSDE EAEAQAAAAV EAPKKTFADL
     GVREELCDAC ENLGYKTATP IQTESIPLAL AGKDIIGLAE TGSGKTAAFV LPILQALLDK
     PQAYFGLIMA PTRELAYQIS QQVDALGSII NVKCATLVGG MDMVPQAIAL SKRPHIIVAS
     PGRLLDHLEN TKGFSLKHLK YLVLDEADRL LDLDFGDSLD KIFKVLPRDD RHTYLFSATM
     SSKVESLQRA ALKNPVRVSI SSSSHQVVST LLQSYMLIPH KYKDLYLIHL LNDNIGHATI
     LFTRTVNETQ RLAVLLRTLG FQALPLHGQL SQSNRLGALN KFKAKARDIL VATDVAARGL
     DIPSVDLVVN FDLPHDSETY VHRVGRTARA GKSGKAVSFV TQYDLEIFQR IEHALGKQVP
     EEKVSRDEVM VYAERVGEAQ RVAVREMKDL HDQRKSGRGG RGGGRGGGRG GRGRGGRRDN
     MDMDEG
//
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