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Database: UniProt
Entry: Q0V9C6_XENTR
LinkDB: Q0V9C6_XENTR
Original site: Q0V9C6_XENTR 
ID   Q0V9C6_XENTR            Unreviewed;       317 AA.
AC   Q0V9C6;
DT   05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT   05-SEP-2006, sequence version 1.
DT   16-OCT-2019, entry version 94.
DE   SubName: Full=SAM pointed domain containing ets transcription factor {ECO:0000313|EMBL:AAI21637.1};
GN   Name=spdef {ECO:0000313|EMBL:AAI21637.1,
GN   ECO:0000313|Ensembl:ENSXETP00000058834,
GN   ECO:0000313|Xenbase:XB-GENE-491205};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus;
OC   Silurana.
OX   NCBI_TaxID=8364 {ECO:0000313|EMBL:AAI21637.1};
RN   [1] {ECO:0000313|EMBL:AAI21637.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6 {ECO:0000313|EMBL:AAI21637.1};
RC   TISSUE=Oviduct {ECO:0000313|EMBL:AAI21637.1};
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSXETP00000058834}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nigerian {ECO:0000313|Ensembl:ENSXETP00000058834};
RX   PubMed=20431018; DOI=10.1126/science.1183670;
RA   Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA   Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L.,
RA   Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E.,
RA   Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T.,
RA   Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M.,
RA   Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N.,
RA   Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D.,
RA   Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B.,
RA   Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M.,
RA   Rokhsar D.S.;
RT   "The genome of the Western clawed frog Xenopus tropicalis.";
RL   Science 328:633-636(2010).
RN   [3] {ECO:0000313|Ensembl:ENSXETP00000058834}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family.
CC       {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AAMC01086980; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC121636; AAI21637.1; -; mRNA.
DR   RefSeq; NP_001072412.1; NM_001078944.1.
DR   STRING; 8364.ENSXETP00000058834; -.
DR   Ensembl; ENSXETT00000064095; ENSXETP00000058834; ENSXETG00000034149.
DR   GeneID; 779866; -.
DR   KEGG; xtr:779866; -.
DR   CTD; 25803; -.
DR   Xenbase; XB-GENE-491205; spdef.
DR   eggNOG; KOG3805; Eukaryota.
DR   eggNOG; ENOG410XSXU; LUCA.
DR   GeneTree; ENSGT00940000157549; -.
DR   KO; K09442; -.
DR   OMA; LDIWKSX; -.
DR   OrthoDB; 908495at2759; -.
DR   TreeFam; TF318679; -.
DR   Proteomes; UP000008143; Unassembled WGS sequence.
DR   Bgee; ENSXETG00000034149; Expressed in 9 organ(s), highest expression level in embryo.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0030154; P:cell differentiation; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008143};
KW   DNA-binding {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019,
KW   ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008143}.
FT   DOMAIN      109    193       PNT. {ECO:0000259|PROSITE:PS51433}.
FT   DOMAIN      231    314       ETS. {ECO:0000259|PROSITE:PS50061}.
SQ   SEQUENCE   317 AA;  35848 MW;  F182270E0E6E6207 CRC64;
     MGSNSASLPP VTHSRLALQD STLTSLDKAS EEGAQGYFLP FCDMLYAGEG GSWAPKGLMP
     VVHRGEGTKE PEQCPVIDSQ GLHHELEYQT SLHLEDHSLE QMQTMVVGEV LKDIETACKL
     LNISADPMEW SAGNVQKWIL WTEHQYRLPQ VGRSFQELTG KDLCALSEDN FRERSPLCGD
     VLYAHLDIWK SAAWMKEKTG PGELRYCGGS GVVGECWADT EVDSSGSGQP IHLWQFLKEL
     LLKPHSYGRS IRWLNKEKGI FKIEDSAQVA RLWGIRKNRP AMNYDKLSRS IRQYYKKGII
     RKPDVSQRLV YQFVHPL
//
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