ID Q0VKV2_ALCBS Unreviewed; 543 AA.
AC Q0VKV2;
DT 05-SEP-2006, integrated into UniProtKB/TrEMBL.
DT 05-SEP-2006, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Medium-chain-fatty-acid CoA ligase {ECO:0000313|EMBL:CAL18196.1};
DE EC=6.2.1.- {ECO:0000313|EMBL:CAL18196.1};
GN Name=alkK {ECO:0000313|EMBL:CAL18196.1};
GN OrderedLocusNames=ABO_2748 {ECO:0000313|EMBL:CAL18196.1};
OS Alcanivorax borkumensis (strain ATCC 700651 / DSM 11573 / NCIMB 13689 /
OS SK2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Alcanivoracaceae; Alcanivorax.
OX NCBI_TaxID=393595 {ECO:0000313|EMBL:CAL18196.1, ECO:0000313|Proteomes:UP000008871};
RN [1] {ECO:0000313|EMBL:CAL18196.1, ECO:0000313|Proteomes:UP000008871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700651 / DSM 11573 / NCIMB 13689 / SK2
RC {ECO:0000313|Proteomes:UP000008871};
RX PubMed=16878126; DOI=10.1038/nbt1232;
RA Schneiker S., Martins dos Santos V.A.P., Bartels D., Bekel T., Brecht M.,
RA Buhrmester J., Chernikova T.N., Denaro R., Ferrer M., Gertler C.,
RA Goesmann A., Golyshina O.V., Kaminski F., Khachane A.N., Lang S., Linke B.,
RA McHardy A.C., Meyer F., Nechitaylo T., Puehler A., Regenhardt D., Rupp O.,
RA Sabirova J.S., Selbitschka W., Yakimov M.M., Timmis K.N., Vorhoelter F.-J.,
RA Weidner S., Kaiser O., Golyshin P.N.;
RT "Genome sequence of the ubiquitous hydrocarbon-degrading marine bacterium
RT Alcanivorax borkumensis.";
RL Nat. Biotechnol. 24:997-1004(2006).
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DR EMBL; AM286690; CAL18196.1; -; Genomic_DNA.
DR RefSeq; WP_011590018.1; NC_008260.1.
DR AlphaFoldDB; Q0VKV2; -.
DR STRING; 393595.ABO_2748; -.
DR KEGG; abo:ABO_2748; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_5_6; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000008871; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd12119; ttLC_FACS_AlkK_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF11; MEDIUM-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CAL18196.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008871}.
FT DOMAIN 30..404
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 455..532
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 543 AA; 59837 MW; 788A3A77E2376282 CRC64;
MSSQVNITRS DSAVESSLVI NHILAAGVLK SPDQTITYGD RTLTYRELNE RIHRLAGVLA
AQGVKPGDTV AVMEWDTNRY LEAFFAIPMM GAVLHTVNVR LSPEQILYTI NHAEDDAILV
NSEFLSTLEE IKDRIETVKT YILLDDSGVK GSDSLPLAGE YEELLAKAPA QYDFPELDEN
TRATTFYTTG TTGLPKGVYF SHRQLVLHTF AARNTIAGVG QGRFNENDVY MPITPMFHVH
AWGIPYMATL MGVKQVYPGR YEPATLLRLL ATHKVTFSHC VPTIIQMLLQ SEAAESVDLS
GWKVIIGGSA LPKAMATKAL KRGIDIYTGY GMSETCPLLT LALLTPELEK AGLETQVDYR
TRTGRPVAMV QLRIVDGEMN DVPHDGESQG EVVVRAPWLT QGYLKDPAKS EELWHGGWLH
TGDVAVMSDD GWLKIVDRIK DVIKTGGEWV SSIDLESLVL QHPGAGECAV VGVPDEKWGE
RPVALVVKNG EVDEDSIKAL VADYAEKGVI SRYGIPDRVI FVDELPRTSV GKLDKKKMRA
EMV
//
